The Human Gut Virome and Its Relationship with Nontransmissible Chronic Diseases.
The Human Gut Virome and Its Relationship with Nontransmissible Chronic Diseases.
复制标题
人类肠道病毒及其与非传染性慢性病的关系
DOI：
10.3390/nu15040977
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发表时间：
2023-02-15
期刊：
影响因子：
5.9
通讯作者：
Aguilar HC
中科院分区：
文献类型：
--
作者：
Ezzatpour S;Mondragon Portocarrero ADC;Cardelle-Cobas A;Lamas A;López-Santamarina A;Miranda JM;Aguilar HC
The human gastrointestinal tract contains large communities of microorganisms that are in constant interaction with the host, playing an essential role in the regulation of several metabolic processes. Among the gut microbial communities, the gut bacteriome has been most widely studied in recent decades. However, in recent years, there has been increasing interest in studying the influences that other microbial groups can exert on the host. Among them, the gut virome is attracting great interest because viruses can interact with the host immune system and metabolic functions; this is also the case for phages, which interact with the bacterial microbiota. The antecedents of virome-rectification-based therapies among various diseases were also investigated. In the near future, stool metagenomic investigation should include the identification of bacteria and phages, as well as their correlation networks, to better understand gut microbiota activity in metabolic disease progression.
