Thermodynamic reversibility of phase transitions. Specific effects of alcohols on phosphatidylcholines.
Thermodynamic reversibility of phase transitions. Specific effects of alcohols on phosphatidylcholines.
复制标题
相变的热力学可逆性。
DOI：
10.1016/0005-2736(85)90248-2
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Rowe,ES
中科院分区：
文献类型：
--
作者：
Rowe,ES
研究了几种磷脂酰乙醇胺（PE）和磷脂酰胆碱（PC）在三种短链醇存在下的凝胶-流体相变。研究了醇对这些转变的热力学可逆性的影响，发现在较高的醇浓度下，PC的转变不具有热力学可逆性。PE的转变在所有酒精浓度下都是热力学可逆的，并且PE不表现出酒精对PC转变温度的双相影响（Rowe， E.S. (1983) Biochemistry 22 3299-3305）。双相转变温度效应和高酒精浓度下PC转变的热力学不可逆性似乎与最近文献报道的完全交叉的凝胶相的诱导相关（Simon， S.A.和McIntosh， T.J. (1984) Biochim）。Biophys。学报，773,169-172)。讨论了这些发现的生物学意义。
The gel-to-fluid phase transitions of several phosphatidylethanolamines (PE's) and phosphatidylcholines (PC's) have been investigated in the presence of three short-chain alcohols. The effects of the alcohols on the thermodynamic reversibility of these transitions was studied and it was found that the transitions for PC's are not thermodynamically reversible at relatively high alcohol concentrations. The PE transitions are thermodynamically reversible for all alcohol concentrations, and the PE's do not exhibit the biphasic effects of alcohol on the transition temperature previously reported for the PC's (Rowe, E.S. (1983) Biochemistry 22 3299–3305). The biphasic transition temperature effects and the thermodynamic irreversibility of PC transitions at high alcohol concentrations appear to be correlated with the induction of a fully interdigitated gel phase recently reported in the literature (Simon, S.A. and McIntosh, T.J. (1984) Biochim. Biophys. Acta 773, 169–172). The biological significance of these findings is discussed.