Policy Statement-Recommendations for the Prevention of Perinatal Group B Streptococcal (GBS) Disease
Policy Statement-Recommendations for the Prevention of Perinatal Group B Streptococcal (GBS) Disease
复制标题
DOI：
10.1542/peds.2011-1466
复制
发表时间：
2011-09-01
期刊：
影响因子：
8
通讯作者：
Watterberg, Kristi L.
中科院分区：
文献类型：
--
作者：
Baker, Carol J.;Byington, Carrie L.;Watterberg, Kristi L.
美国疾病控制与预防中心 (CDC) 预防围产期 B 型链球菌 (GBS) 疾病的指南最初于 1996 年发布。美国儿科学会 (AAP) 也在 1997 年发布了关于该主题的政策声明。2002 年，CDC 发布了修订后的指南，建议普遍进行产前 GBS 筛查； AAP 认可了这些指南，并在 2003 年红皮书中发布了基于这些指南的建议。自此，新生儿早发 GBS 疾病的发病率估计下降了 80%。然而，2010年，GBS疾病仍然是早发新生儿败血症的主要原因。 CDC 根据对 2002 年之后生成的数据的评估，于 2010 年发布了修订后的指南。这些修订后的综合指南已得到 AAP 的认可，重申了主要的预防策略——对培养阳性和高危妇女进行产前 GBS 筛查和产时抗生素预防——并包括关于妊娠期间 GBS 定植鉴定的实验室方法的新建议、 对早产和胎膜早破的妇女进行筛查和产时预防，对青霉素过敏的妇女更新预防建议，并修订新生儿护理流程。本政策声明的目的是回顾和讨论 2002 年和 2010 年 CDC 指南之间与儿科实践最相关的差异。儿科2011; 128：611-616
The Centers for Disease Control and Prevention (CDC) guidelines for the prevention of perinatal group B streptococcal (GBS) disease were initially published in 1996. The American Academy of Pediatrics (AAP) also published a policy statement on this topic in 1997. In 2002, the CDC published revised guidelines that recommended universal antenatal GBS screening; the AAP endorsed these guidelines and published recommendations based on them in the 2003 Red Book. Since then, the incidence of early-onset GBS disease in neonates has decreased by an estimated 80%. However, in 2010, GBS disease remained the leading cause of early-onset neonatal sepsis. The CDC issued revised guidelines in 2010 based on evaluation of data generated after 2002. These revised and comprehensive guidelines, which have been endorsed by the AAP, reaffirm the major prevention strategy-universal antenatal GBS screening and intrapartum antibiotic prophylaxis for culture-positive and high-risk women-and include new recommendations for laboratory methods for identification of GBS colonization during pregnancy, algorithms for screening and intrapartum prophylaxis for women with preterm labor and premature rupture of membranes, updated prophylaxis recommendations for women with a penicillin allergy, and a revised algorithm for the care of newborn infants. The purpose of this policy statement is to review and discuss the differences between the 2002 and 2010 CDC guidelines that are most relevant for the practice of pediatrics. Pediatrics 2011; 128: 611-616