Benign paroxysmal torticollis: phenotype, natural history, and quality of life.
Benign paroxysmal torticollis: phenotype, natural history, and quality of life.
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DOI:
10.1038/s41390-020-01309-1
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发表时间:
2021-11
影响因子:
3.6
通讯作者:
Gelfand AA
中科院分区:
文献类型:
--
作者:
Greene KA;Lu V;Luciano MS;Qubty W;Irwin SL;Grimes B;Gelfand AA
Benign paroxysmal torticollis (BPT) is characterized by attacks of head tilt associated with vomiting, irritability, and/or ataxia in early childhood. BPT is associated with migraine but risk factors are unknown. Impact on quality of life is also unknown. Parents/caregivers of children with ongoing or resolved BPT participated in telephone interviews (n = 73). Those with ongoing BPT completed the Infant Toddler Quality of Life questionnaire (ITQoL). Median age of children at the time of interview was 2.9 years (range 0.25–23). BPT was ongoing in 52% (n = 38). Nineteen percent (n = 14) developed migraine (median age 9.25 years, range 2.5–23) and 63% (n = 46) developed another episodic syndrome associated with migraine. Proportion of patients who developed migraine was higher among those with certain migrainous symptoms during BPT attacks vs. those without: phonophobia (58 vs. 21%, p = 0.02), photophobia and phonophobia (55 vs. 23%, p = 0.05), and photophobia, phonophobia, and motion sensitivity (60 vs. 22%, p = 0.02). ITQoL results showed significant impact of BPT on quality of life. Children with BPT may develop migraine or other episodic syndromes associated with migraine. Presence of migrainous features during BPT episodes may increase likelihood of developing migraine. Though characterized as “benign,” BPT can significantly impact children and families.
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