Reengineering clinical research with informatics

Reengineering clinical research with informatics
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DOI:
10.2310/6650.2006.06014
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发表时间:
2006-09-01
影响因子:
2.6
通讯作者:
Johnson, Stephen B.
Johnson, Stephen B.
中科院分区:
医学4区
文献类型:
--
作者:
Chung, Thomas K.;Kukafka, Rita;Johnson, Stephen B.

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转化研究领域未来的成功取决于临床研究企业突破限制其生产力的障碍的能力。随着更多基础科学发现的出现,我们能否有效地将这些知识转化为改善患者护理的能力完全取决于我们回答临床问题的方式。信息学——有效利用信息的科学——有望帮助推进科学行为。然而,将信息学融入企业也面临着一系列挑战。为了利用改进信息使用的好处,首先确定信息在研究中的流动方式非常重要。信息学的深思熟虑的实施——考虑到社会和组织的细微差别——无疑将带来一个更加高效和有效的临床研究企业。
The future success of the translational research spectrum depends on the clinical research enterprise's ability to break through the barriers that constrain its productivity. As more basic science discoveries emerge, our ability to effectively translate this knowledge into improved patient care rests squarely on the manner in which we answer clinical questions. Informatics-the science of effective information use-is poised to help advance the conduct of science. However, incorporating informatics into the enterprise comes with its own set of challenges. To harness the benefits of improved information use, it is important to first establish how information flows within research. A thoughtful implementation of informatics-one that factors in social and organizational nuances-will undoubtedly lead to a more efficient and effective clinical research enterprise.