Multimorbidity of non-communicable diseases in low-income and middle-income countries: a systematic review and meta-analysis.
Multimorbidity of non-communicable diseases in low-income and middle-income countries: a systematic review and meta-analysis.
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DOI：
10.1136/bmjopen-2021-049133
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发表时间：
2022-01-21
期刊：
影响因子：
2.9
通讯作者：
Klipstein-Grobusch K
中科院分区：
文献类型：
--
作者：
Asogwa OA;Boateng D;Marzà-Florensa A;Peters S;Levitt N;van Olmen J;Klipstein-Grobusch K
多发性硬化症是一项重大的公共卫生挑战，在低/中等收入国家的发病率不断上升。本审查旨在系统地综合证据，说明居住在中低收入国家的成年人中非传染性疾病（NCDs）多重发病率的患病率、模式和相关因素。我们对报告低收入国家18岁以上成年人非传染性疾病的患病率、决定因素和多种发病模式的文章进行了系统回顾和荟萃分析。对于PROSPERO注册综述，我们检索了PubMed、EMBASE和科克伦图书馆2009年至2020年5月30日发表的文章。如果研究报告了关于中低收入国家成年人多种非传染性疾病的原始研究，则纳入研究。系统检索共获得3272篇文献，纳入39篇文献，共1220309例受试者。大多数研究使用了来自健康调查的自我报告数据。多发性骨髓瘤的患病率差异很大; 0.7%-81.3%，合并患病率为36.4%（95% CI 32.2%-40.6%）。多发病率随年龄增加而增加，随机效应荟萃分析显示，女性，OR（95%CI）：1.48，1.33至1.64，富裕，1.35（1.02至1.80），城市居住，1.10（1.01至1.20），分别与NCD多发病率较高的几率相关。最常见的多发病模式包括心脏代谢和心肺疾病。在老年人、妇女、富裕人群和城市居民中发病率较高的低收入国家，多种形式的非传染性疾病是一个重要问题。需要纵向数据来了解多重危机的真正方向及其决定因素，确定因果关系，并确定趋势和模式如何随着时间的推移而变化。CRD 42019133453。
Multimorbidity is a major public health challenge, with a rising prevalence in low/middle-income countries (LMICs). This review aims to systematically synthesise evidence on the prevalence, patterns and factors associated with multimorbidity of non-communicable diseases (NCDs) among adults residing in LMICs. We conducted a systematic review and meta-analysis of articles reporting prevalence, determinants, patterns of multimorbidity of NCDs among adults aged >18 years in LMICs. For the PROSPERO registered review, we searched PubMed, EMBASE and Cochrane libraries for articles published from 2009 till 30 May 2020. Studies were included if they reported original research on multimorbidity of NCDs among adults in LMICs. The systematic search yielded 3272 articles; 39 articles were included, with a total of 1 220 309 participants. Most studies used self-reported data from health surveys. There was a large variation in the prevalence of multimorbidity; 0.7%–81.3% with a pooled prevalence of 36.4% (95% CI 32.2% to 40.6%). Prevalence of multimorbidity increased with age, and random effect meta-analyses showed that female sex, OR (95% CI): 1.48, 1.33 to 1.64, being well-off, 1.35 (1.02 to 1.80), and urban residence, 1.10 (1.01 to 1.20), respectively were associated with higher odds of NCD multimorbidity. The most common multimorbidity patterns included cardiometabolic and cardiorespiratory conditions. Multimorbidity of NCDs is an important problem in LMICs with higher prevalence among the aged, women, people who are well-off and urban dwellers. There is the need for longitudinal data to access the true direction of multimorbidity and its determinants, establish causation and identify how trends and patterns change over time. CRD42019133453.
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DOI：
10.5530/ijmedph.2016.2.5
发表时间：
2016-04
期刊：
International journal of medicine and public health
影响因子：
--
作者：
Agrawal S;Agrawal PK
通讯作者：
Agrawal PK
影响因子：
24
作者：
Carter, Paul;Lagan, Jakub;Miller, Christopher A.
通讯作者：
Miller, Christopher A.
影响因子：
3.3
作者：
Hien, Herve;Berthe, Abdramane;Macq, Jean
通讯作者：
Macq, Jean
影响因子：
4.3
作者：
Hidalgo CA;Blumm N;Barabási AL;Christakis NA
通讯作者：
Christakis NA
影响因子：
5.2
作者：
Jankovic, J.;Mirkovic, M.;Terzic-Supic, Z.
通讯作者：
Terzic-Supic, Z.