STUDIES ON CATABOLISM OF NG-METHYLARGININE, NG,N'G-DIMETHYLARGININE AND NG,NG-DIMETHYLARGININE IN RABBIT
STUDIES ON CATABOLISM OF NG-METHYLARGININE, NG,N'G-DIMETHYLARGININE AND NG,NG-DIMETHYLARGININE IN RABBIT
复制标题
DOI：
10.1042/bj1540179
复制
发表时间：
1976-01-01
影响因子：
4.1
通讯作者：
MCDERMOTT, JR
中科院分区：
文献类型：
--
作者：
MCDERMOTT, JR
1.在家兔体内研究了Ng-methylarginine、Ng，Ng-dimethylarginine和Ng，Ng-dimethylarginine的消除途径。2.分析表明，这些氨基酸的血浆浓度较低（约1 nmol/ml），其比例与组织蛋白中发现的相似。脑、肾、肝和脾提取物中这些氨基酸的浓度相似，除了肝具有较低浓度的Ng-甲基精氨酸和Ng，Ng-二甲基精氨酸。脑脊液中含有微量的氨基酸。
1. The routes of elimination of Ng-methylarginine, Ng, Ng-dimethylarginine and Ng, Ng-dimethylarginine were investigated in the rabbit. 2. Analyses showed low plasma concentrations of these amino acids (around 1 nmol/ml) and ratios similar to those found in tissue proteins. The concentrations of these amino acids in extracts of brain, kidney, liver and spleen were similar except that liver had a lower concentration of Ng-methylarginine and Ng, Ng-dimethylarginine. Cerebrospinal fluid contained traces of each amino acid.