CIRCADIAN AND ULTRADIAN RHYTHMS IN PERIOD MUTANTS OF DROSOPHILA-MELANOGASTER
CIRCADIAN AND ULTRADIAN RHYTHMS IN PERIOD MUTANTS OF DROSOPHILA-MELANOGASTER
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DOI：
10.1007/bf01066008
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发表时间：
1987-01-01
影响因子：
2.6
通讯作者：
RINGO, JM
中科院分区：
文献类型：
--
作者：
DOWSE, HB;HALL, JC;RINGO, JM
使用数字技术进行信号分析。sbd。相关图和时间序列的高分辨率分析，最大熵谱分析（MESA）。sbd。我们在自由奔跑的 per0 雄性和缺乏 per 位点的雌性的运动活动中检测到了昼夜节律和超昼夜节律（per-；杂合的两个缺陷，每个缺陷都删除了该基因）。超过一半的 per0 个体和一半的测试个体有节律性活跃，主导周期为 4 至 22 小时；大多数有明显节律的 per0 和 perflies 明显表现出多重周期性。这种新颖的节律行为模式与野生型模式完全不同。我们的观察提出的一个假设是，per+基因产物介导多个超电振荡器的耦合以产生野生型昼夜节律。
Using digital techniques for signal analysis.sbd.the correlogram and a high-resolution analysis of time series, maximum-entropy spectral analysis (MESA).sbd.we have detected both circadian and ultradian rhythms in the locomotor activity of free-running per0 males and in females lacking the per locus (per-; heterozygous for two deficiencies, each of which deletes the gene). Over half the per0 individuals and half the per- individuals tested were rhythmically active, with dominant periods ranging from 4 to 22 h; most of the significantly rhythmic per0 and per- flies clearly exhibited multiple periodicities. This novel pattern of rhythmic behavior is thoroughly distinct from the wild-type pattern. One hypothesis suggested by our observations is that the per+ gene products mediate the coupling of multiple ultradian oscillators to produce wild-type circadian rhythms.