Low p53 positivity in verrucous skin lesion in diabetic neuropathy occurring on the dorsum of the foot.
Low p53 positivity in verrucous skin lesion in diabetic neuropathy occurring on the dorsum of the foot.
复制标题
足背糖尿病神经病变的疣状皮肤病变中 p53 阳性率低。
DOI：
10.1111/j.1365-4632.2011.04891.x
复制
发表时间：
2013
期刊：
影响因子：
3.6
通讯作者：
Okuyama R.
中科院分区：
文献类型：
--
作者：
Ashida A;Kiniwa Y;Kobayashi A;Matsumoto K;Okuyama R.
本文介绍了一例51岁男性因右足背疣皮损而转诊至医院的病例。患者有10年的非胰岛素依赖型糖尿病神经病变和视网膜病变病史。患者P53阳性细胞率不到10%。文章讨论了糖尿病神经病变(VSLDN)足部疣状皮肤病变，以及抑制蛋白P53如何有助于VSLDN的鉴别诊断。
The article presents a case study of a 51-year-old man referred to the hospital due to verrucous skin lesion on the dorsum of the right foot. Patient had a 10-year history of non-insulin-dependent diabetes mellitus with neuropathy and retinopathy. The ratio of the p53-positive cells of the patient was less than 10 percent. The article discusses verrucous skin lesions on the feet in diabetic neuropathy (VSLDN), and how the suppressor protein, p53, aids in the differential diagnosis of VSLDN.