EFFECTS OF PRIOR SUSTAINED TACTILE STIMULATION ON THE SOMATOSENSORY RESPONSE TO THE SUDDEN CHANGE OF INTENSITY IN HUMANS: AN MAGNETOENCEPHALOGRAPHY STUDY
EFFECTS OF PRIOR SUSTAINED TACTILE STIMULATION ON THE SOMATOSENSORY RESPONSE TO THE SUDDEN CHANGE OF INTENSITY IN HUMANS: AN MAGNETOENCEPHALOGRAPHY STUDY
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DOI：
10.1016/j.neuroscience.2011.03.019
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发表时间：
2011-05-19
期刊：
影响因子：
3.3
通讯作者：
Kakigi, R.
中科院分区：
文献类型：
--
作者：
Otsuru, N.;Inui, K.;Kakigi, R.
快速发现感觉变化对生存很重要。变化检测系统应该与记忆密切相关，因为它需要大脑从过去的感觉状态中分离出新的刺激。为了阐明过去的感觉状态对人体体感皮层处理的影响，用脑磁图（MEG）记录了大脑对施加于手部的一系列电脉冲强度突然变化的反应。在实验1中，我们考察了条件反射和测试刺激之间的偏差幅度（1.0、0.5、0.3、0.2和0.1 mA）的影响。实验2考察条件刺激持续时间（3、1.5、1.0和0.5 s）的影响。刺激强度的突变激活了对侧初级（cSI）和次级体感皮层（cSII）。cSI和cSII活动的幅度不仅取决于强度变化的幅度，而且取决于变化之前条件刺激的长度，这表明先前触觉信息的存储参与了这些反应的产生。我们还讨论了在变化相关的活动中，有一种开始活动（没有条件刺激）参与的可能性。(c) 2011 ibro。Elsevier Ltd.出版。版权所有。
The rapid detection of sensory changes is important to survival. The change-detection system should relate closely to memory since it requires the brain to separate a new stimulus from past sensory status. To clarify effects of past sensory status on processing in the human somatosensory cortex, brain responses to an abrupt change of intensity in a train of electrical pulses applied to the hand were recorded by magnetoencephalography (MEG). In Experiment 1, effects of the magnitude of deviance (1.0, 0.5, 0.3, 0.2, and 0.1 mA) between conditioning and test stimuli were examined. In Experiment 2, effects of the duration of the conditioning stimulus (3, 1.5, 1.0, and 0.5 s) were examined. The abrupt change in stimulus intensity activated the contralateral primary (cSI) and secondary somatosensory cortex (cSII. The amplitude of the cSI and cSII activity was dependent on not only the magnitude of the change in intensity but also the length of the conditioning stimulus prior to the change, suggesting that storage of prior tactile information was involved in generating these responses. The possibility that an activity of onset (with no conditioning stimulus) would be involved in the change-related activity was also discussed. (C) 2011 IBRO. Published by Elsevier Ltd. All rights reserved.