Cancer disparities: unmet challenges in the elimination of disparities.
Cancer disparities: unmet challenges in the elimination of disparities.
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DOI：
10.1158/1055-9965.epi-11-0628
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发表时间：
2011-09
期刊：
影响因子：
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通讯作者：
Colditz GA
中科院分区：
文献类型：
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作者：
Gehlert S;Colditz GA
《癌症流行病学、生物标志物与预防》出版的头 20 年是在人们越来越关注健康差异以及对其决定因素的了解不断进步的时期。然而，尽管有关于差异的明确记录和对决定因素的深入了解，我们在减少人口层面的差异方面几乎没有取得任何进展。多层次模型，例如由人口健康和健康差异中心 (CPHHD) 制作的模型，有望了解癌症差异的复杂决定因素及其相互作用，并将科学发现转化为解决方案。 CPHHD 模型涵盖了从生物学到社会学的一系列科学学科，每个学科都有自己的学科语言和方法。跨学科界限有效工作的能力对于制定全面的解决方案至关重要。在简要描述了当前有关健康差异的知识状况后，我们概述了差异研究人员和从业者面临的三大挑战，并提出了应对这些挑战的建议。这些挑战包括如何在差异研究中考虑种族和族裔、如何最好地将发现转化为癌症差异的公共卫生解决方案，以及如何创建支持成功执行多层次研究的研究环境。为了推进我们消除癌症差异的努力，迫切需要关注上述所有三个挑战。解决上述挑战将有助于消除未来的差距。
The first 20 years of publication of Cancer Epidemiology, Biomarkers & Prevention occurred during a period of increased attention to health disparities and advances in knowledge about their determinants. Yet, despite clear documentation of disparities and advanced understanding of determinants, we have made little headway in reducing disparities at the population level. Multilevel models, such as one produced by the Centers for Population Health and Health Disparities (CPHHD), hold promise for understanding the complex determinants of cancer disparities and their interactions as well as translating scientific discoveries into solutions. The CPHHD model maps across a range of scientific disciplines, from the biological to the social, each with its own disciplinary language and methods. The ability to work effectively across disciplinary boundaries is essential to framing comprehensive solutions. After briefly characterizing the current state of knowledge about health disparities, we outline three major challenges faced by disparities researchers and practitioners and offer suggestions for addressing these challenges. These challenges are how to consider race and ethnicity in disparities research, how best to translate discoveries into public health solutions to cancer disparities, and how to create a research environment that supports the successful execution of multilevel research. Attention to all three of the challenges outlined above is urgently needed to advance our efforts to eliminate cancer disparities. Addressing the challenges outlined above will help to eliminate disparities in the future.