Recent development on peptide-based probes for multifunctional biomedical imaging
Recent development on peptide-based probes for multifunctional biomedical imaging
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用于多功能生物医学成像的基于肽的探针的最新进展
DOI：
10.1016/j.cclet.2018.03.032
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发表时间：
2018
影响因子：
9.1
通讯作者：
Sun Yao
中科院分区：
文献类型：
--
作者：
Xu Yuling;Tian Mei;Zhang Hong;Xiao Yuling;Hong Xuechuan;Sun Yao
肽基探针具有生物相容性高、排泄速度快、药代动力学好、制备简单、稳受性好等优点，在生物医学研究中发挥着重要作用。考虑到将成像探针转化为临床应用，基于肽的探针仍然是最理想和最佳的候选者。本文综述了肽基探针在生物医学成像方面的研究进展，并重点介绍了其在生物医学成像方面的成功应用。
Peptide-based probes play prominent roles in biomedical research due to their promising properties such as high biocompatibility, fast excretion, favorable pharmacokinetics as well as easy and robust preparation. Considering the translation of imaging probes into clinical applications, peptide-based probes remain to be the most desirable and optimal candidates. This review summarized the development of peptide-based probes with promising imaging modalities and highlighted the successful applications forin vivobiomedical imaging.