Effect of functional yogurt NY-YP901 in improving the trait of metabolic syndrome
Effect of functional yogurt NY-YP901 in improving the trait of metabolic syndrome
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DOI：
10.1038/ejcn.2011.115
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发表时间：
2011-11-01
影响因子：
4.7
通讯作者：
Chang, D. K.
中科院分区：
文献类型：
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作者：
Chang, B. J.;Park, S. U.;Chang, D. K.
背景/目的：本研究旨在评估功能性酸奶NY-YP 901（Namyang Dairy Product Co. Ltd和Nutra R&BT Inc.，首尔，韩国）添加嗜热链球菌、嗜酸乳杆菌、双歧杆菌的混合物和含有短双歧杆菌（CBG-C2）、粪肠球菌FK-23、纤维溶胶-2等的额外成分。治疗组和对照组分别每天两次食用功能性酸奶NY-YP 901（150 ml）和安慰剂酸奶，持续8周。治疗前后分别测量体重、体重指数（BMI）、血压、血脂、空腹血糖、糖化血红蛋白（HbA 1C）、腰围。纳入标准为年龄在20-65岁之间的健康个体，他们提交了知情同意书。结果：在2009年8月至2009年12月期间，101名健康参与者（31名男性和70名女性）完成了研究。治疗组53例，对照组48例。在服用NY-YP 901的治疗组中，观察到体重出现统计学显着的有益变化（治疗组vs对照组-0.24 +/- 1.50 vs +0.64 +/- 1.39 kg，P
Background/Objectives: This study was aimed to assess the beneficial effects on metabolic syndrome of functional yogurt NY-YP901 (Namyang Dairy Product Co. Ltd and Nutra R&BT Inc., Seoul, Korea) supplemented with mixture of Streptococcus thermophilus, Lactobacillus acidophilus, Bifidobacterium infantis and extra-ingredients containing Bifidobacterium breve (CBG-C2), Enterococcus faecalis FK-23, fibersol-2 and so on.Subjects/Methods: This study was designed as an 8-week randomized, double-blind, placebo-controlled, parallel study. Treatment and control groups consumed a functional yogurt NY-YP901 (150 ml) and a placebo yogurt twice a day, respectively, for 8 weeks. Body weight and body mass index (BMI), blood pressure, lipid profiles, fasting glucose with HbA1C and waist circumference were measured before and after treatment. Inclusion criteria were healthy individuals between the ages 20-65 years old who submitted an informed consent.Results: During the period August 2009 to December 2009, 101 healthy participants (31 males and 70 females) finished the study. Treatment group were 53 individuals, and the control group were 48 individuals. In the treatment group consuming NY-YP901, statistically significant beneficial changes were observed in body weight (treatment group vs control group-0.24 +/- 1.50 vs +0.64 +/- 1.39 kg, P