Widespread sexual disruption in wild fish
Widespread sexual disruption in wild fish
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DOI：
10.1021/es9710870
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发表时间：
1998-09-01
影响因子：
11.4
通讯作者：
Sumpter, JP
中科院分区：
文献类型：
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作者：
Jobling, S;Nolan, M;Sumpter, JP
环境中存在的一些化学品已被证明可以模拟或拮抗类固醇激素的作用，这一问题通常被称为“内分泌干扰/调节”。然而，很少有证据支持这一假设，即接触干扰内分泌的化学品是一个全球性的环境健康问题。在本文中，我们证明了高发病率的间性在整个英国的野生种群的河流鱼类（蟑螂，红鲤）。这些生殖障碍与暴露于生殖活性物质相一致，并与已知含有雌激素化学物质的污水处理厂的排放物有关。这是第一个记录在案的例子，一个广泛的性破坏野生种群的任何脊椎动物，并表明生殖和发育的影响确实导致暴露于环境水平的化学品存在于典型的英国河流。
A number of chemicals present in the environment have been shown to mimic or antagonize the actions of steroid hormones, an issue often described as "endocrine disruption/modulation". There is very little evidence, however, to support the hypothesis that exposure to endocrine-disrupting chemicals is a global environmental health problem. In this paper, we demonstrate a high incidence of intersexuality in wild populations of riverine fish (roach; Rutilus rutilus) throughout the United Kingdom. These reproductive disturbances are consistent with exposure to hormonally active substances and a re associated with discharges from sewage treatment works that are known to contain estrogenic chemicals. This is the first documented example of a widespread sexual disruption in wild populations of any vertebrate and indicates that reproductive and developmental effects do result from exposure to ambient levels of chemicals present in typical British rivers.