Relationship between longitudinal and radial contractility in subclinical diabetic heart disease
Relationship between longitudinal and radial contractility in subclinical diabetic heart disease
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DOI：
10.1042/cs20030153
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发表时间：
2004-01-01
期刊：
影响因子：
6
通讯作者：
Marwick, TH
中科院分区：
文献类型：
--
作者：
Fang, ZY;Leano, R;Marwick, TH
亚临床左心室（W）功能障碍可以通过纵向收缩减少来识别。通过多巴酚丁胺超声心动图评估，我们试图确定53例无左室肥厚、射血分数正常和无缺血的糖尿病患者亚临床左室功能障碍对桡动脉收缩力的影响，并与年龄匹配的对照组进行比较。在胸骨旁视图中测量中后壁和中前间隔壁的径向峰值心肌收缩速度（S-m）和舒张早期速度（E-m）、应变和应变率，并对个体患者的每个变量（径向收缩力）取平均值。这些变量也在心尖长轴视图中的中后壁和中前间隔壁中测量，并对个体患者的每个变量取平均值（纵向收缩力）。糖尿病患者的平均桡骨S-m、应变和应变率（分别为2.9+/-0.6 cm/s，28+/-5%和1.8+/-0.4 s（-1））显著高于对照组（分别为2.4+/-0.7 cm/s，23+/-4%和1.6+/-0.3 s（-1）;所有P
Subclinical left ventricular (W) dysfunction may be identified by reduced longitudinal contraction. We sought to define the effects of subclinical LV dysfunction on radial contractility in 53 patients with diabetes mellitus with no LV hypertrophy, normal ejection fraction and no ischaemia as assessed by dobutamine echocardiography, in comparison with age-matched controls. Radial peak myocardial systolic velocity (S-m) and early diastolic velocity (E-m), strain and strain rate were measured in the mid-posterior and mid-anteroseptal walls in parasternal views and each variable was averaged for individual patients (radial contractility). These variables were also measured in the mid-posterior and mid-anteroseptal walls in the apical long-axis view and each variable was averaged for individual patients (longitudinal contractility). Mean radial S-m, strain and strain rate were significantly increased in diabetic patients (2.9+/-0.6 cm/s, 28+/-5% and 1.8+/-0.4 s(-1) respectively) compared with controls (2.4+/-0.7 cm/s, 23+/-4% and 1.6+/-0.3 s(-1) respectively; all P