Multistep DNA-Templated Reactions for the Synthesis of Functional Sequence Controlled Oligomers
Multistep DNA-Templated Reactions for the Synthesis of Functional Sequence Controlled Oligomers
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DOI：
10.1002/anie.201002721
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发表时间：
2010-01-01
影响因子：
16.6
通讯作者：
O'Reilly, Rachel K.
中科院分区：
文献类型：
--
作者：
McKee, Mireya L.;Milnes, Phillip J.;O'Reilly, Rachel K.
仿生：设计链置换机制以允许以 DNA 为模板合成任意长度的功能性寡聚物（参见方案）。该机制的关键特征是连续的偶联反应在几乎相同的环境中发生，并且仅在最后的合成步骤中需要纯化。 © 2010 WILEY-VCH Verlag GmbH and Co. KGaA，魏因海姆。
Biomimetic: A strand displacement mechanism was designed to permit DNA-templated synthesis of functional oligomers of arbitrary length (see scheme). Key features of the mechanism are that successive coupling reactions take place in near-identical environments and that purification is only necessary in the last synthesis step. © 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.