LIPOFUSCIN OF HUMAN RETINAL-PIGMENT EPITHELIUM
LIPOFUSCIN OF HUMAN RETINAL-PIGMENT EPITHELIUM
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DOI：
10.1016/s0002-9394(14)75193-1
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发表时间：
1980-01-01
影响因子：
4.2
通讯作者：
ROTHMAN, H
中科院分区：
文献类型：
--
作者：
FEENEYBURNS, L;BERMAN, ER;ROTHMAN, H
人视网膜色素上皮的氯仿-甲醇提取物的荧光光谱分析证实了老年人色素上皮中脂褐素色素的存在。年轻个体的色素上皮中的类似组分的光谱分析的数量不足。这些眼睛的色素上皮的EM显示年轻的眼睛很少或没有脂褐素颗粒，但在老年人的眼睛大量。
Analysis of the fluorescent spectra of chloroform-methanol extracts of human retinal pigment epithelium confirmed the presence of lipofuscin pigments in the pigment epithelium of older individuals. Similar fractions in the pigment epithelium of young individuals were present in insufficient quantities for spectral analysis. EM of the pigment epithelium of these eyes showed few or no lipofuscin granules in young eyes but large numbers in older eyes.