Photothermal Modeling and Analysis of Intrabody Terahertz Nanoscale Communication

Photothermal Modeling and Analysis of Intrabody Terahertz Nanoscale Communication
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DOI:
10.1109/tnb.2017.2757906
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发表时间:
2017-09
影响因子:
3.9
通讯作者:
Hadeel Elayan;Pedram Johari;R. Shubair;J. Jornet
Hadeel Elayan;Pedram Johari;R. Shubair;J. Jornet
中科院分区:
生物学3区
文献类型:
--
作者:
Hadeel Elayan;Pedram Johari;R. Shubair;J. Jornet

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植入的纳米生物传感器之间的无线通信将实现智能健康监测和诊断系统的变革。纳米电子学和纳米光子学的最新技术将太赫兹(THz)波段(0.1-10太赫兹)和光学波段(红外,30-400太赫兹,可见光,400-750太赫兹)作为纳米生物传感器之间通信的频率范围。近年来,为了研究和评估体内电磁纳米级通信的可行性,已经建立了几种传播模型。这些工作主要集中在了解EM信号通过生物介质的传播,但没有捕捉到由此产生的光热效应及其对通信以及对身体本身的影响。本文基于扩散热流理论,建立了一种新的体内通信热噪声模型。特别地,提出了一个分析框架来说明人体中的分子如何从电磁场中吸收能量,并随后将这种能量作为热量释放到它们的周围环境。结果,观察到温度的变化,由此可以计算分子吸收噪声。这种分析从健康和传播的角度来看有双重好处。对于医学界来说,所提出的方法允许对太赫兹频率吸收引起的温度升高进行量化。为了通信的目的,对体内介质的全面理解为开发适合纳米机器能力的调制打开了大门,并为太赫兹波段通道和光学窗口的特性量身定制。
Wireless communication among implanted nano-biosensors will enable transformative smart health monitoring and diagnosis systems. The state of the art of nano-electronics and nano-photonics points to the terahertz (THz) band (0.1–10 THz) and optical frequency bands (infrared, 30–400 THz, and visible, 400–750 THz) as the frequency range for communication among nano-biosensors. Recently, several propagation models have been developed to study and assess the feasibility of intra-body electromagnetic (EM) nanoscale communication. These works have been mainly focused on understanding the propagation of EM signals through biological media, but do not capture the resulting photothermal effects and their impact both on the communication as well as on the body itself. In this paper, a novel thermal noise model for intra-body communication based on the diffusive heat flow theory is developed. In particular, an analytical framework is presented to illustrate how molecules in the human body absorb energy from EM fields and subsequently release this energy as heat to their immediate surroundings. As a result, a change in temperature is witnessed from which the molecular absorption noise can be computed. Such analysis has a dual benefit from a health as well as a communication perspective. For the medical community, the presented methodology allows the quantization of the temperature increase resulting from THz frequency absorption. For communication purposes, the complete understanding of the intra-body medium opens the door toward developing modulations suited for the capabilities of nano-machines and tailored to the peculiarities of the THz band channel as well as the optical window.