Computational Cardiovascular Flow Analysis with the Variational Multiscale Methods
Computational Cardiovascular Flow Analysis with the Variational Multiscale Methods
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DOI：
10.25073/jaec.201932.245
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发表时间：
2019-06
期刊：
影响因子：
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通讯作者：
K. Takizawa;Y. Bazilevs;T. Tezduyar;M. Hsu
中科院分区：
文献类型：
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作者：
K. Takizawa;Y. Bazilevs;T. Tezduyar;M. Hsu
计算心血管流量分析可以为医生提供有价值的信息，在广泛的患者特定的情况下，包括脑动脉瘤，动脉瘤和心脏瓣膜。在这类流动分析中面临的计算挑战也有很大的范围。它们包括不稳定流动、复杂的心血管几何形状、移动边界和界面（例如心脏瓣膜小叶的运动）、移动固体表面之间的接触（例如小叶之间的接触）以及血液与心血管结构之间的流体-结构相互作用。这些挑战中的许多已经或正在解决的时空变分多尺度（ST-VMS）方法，任意拉格朗日-欧拉VMS（ALE-VMS）方法，和基于VMS的沉浸几何分析（IMGA-VMS），作为核心计算方法，以及与它们结合使用的特殊方法。我们提供了一个核心和特殊方法的概述，并提出了具有挑战性的计算与这些方法，包括主动脉和心脏瓣膜流量分析的例子。这是一篇开放获取的文章，根据知识共享署名许可证（http：//creativecommons.org/licenses/by/4.0/）的条款分发，该许可证允许在任何媒体上不受限制地使用，分发和复制原始作品。
Computational cardiovascular flow analysis can provide valuable information to medical doctors in a wide range of patientspecific cases, including cerebral aneurysms, aortas and heart valves. The computational challenges faced in this class of flow analyses also have a wide range. They include unsteady flows, complex cardiovascular geometries, moving boundaries and interfaces, such as the motion of the heart valve leaflets, contact between moving solid surfaces, such as the contact between the leaflets, and the fluid–structure interaction between the blood and the cardiovascular structure. Many of these challenges have been or are being addressed by the Space–Time Variational Multiscale (ST-VMS) method, Arbitrary Lagrangian–Eulerian VMS (ALE-VMS) method, and the VMS-based Immersogeometric Analysis (IMGA-VMS), which serve as the core computational methods, and the special methods used in combination with them. We provide an overview of the core and special methods and present examples of challenging computations carried out with these methods, including aorta and heart valve flow analyses. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.