GAUGING THE LIKELIHOOD OF CAVITATION FROM SHORT-PULSE, LOW-DUTY CYCLE DIAGNOSTIC ULTRASOUND
GAUGING THE LIKELIHOOD OF CAVITATION FROM SHORT-PULSE, LOW-DUTY CYCLE DIAGNOSTIC ULTRASOUND
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DOI：
10.1016/0301-5629(91)90125-g
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发表时间：
1991-01-01
影响因子：
2.9
通讯作者：
HOLLAND, CK
中科院分区：
文献类型：
--
作者：
APFEL, RE;HOLLAND, CK
尽管在流行病学研究和广泛的临床应用调查中没有发现诊断性超声的有害影响（Ziskin和Petitti 1988），但在对诊断性超声应用相关的潜在风险进行总体评估时，必须调查瞬时空化发生的条件。本文将Holland和Apfel（1989）提出的近似理论的结果扩展到核群，以预测具有与生物流体相似物理性质的宿主流体中空化的发生。根据这一分析和最近的体外空化实验结果，开发了一个指数，可以衡量在短脉冲、低占空比诊断超声存在下大量微泡生长的可能性。
Although no deleterious effects from diagnostic ultrasound have been reported in epidemiologic studies and surveys of widespread clinical usage (Ziskin and Petitti 1988), the conditions for the onset of transient cavitation must be investigated in the total evaluation of potential risks associated with diagnostic ultrasound applications. An extension of the results from the approximate theory developed by Holland and Apfel (1989) is applied in this paper to a population of nuclei to predict the onset of cavitation in host fluids with physical properties similar to those of biological fluids. From this analysis and from results of recent in vitro cavitation experiments, an index is developed which can gauge the likelihood of substantial microbubble growth in the presence of short-pulse, low-duty cycle diagnostic ultrasound.