HELICAL AND RETROGRADE SECONDARY FLOW PATTERNS IN THE AORTIC-ARCH STUDIED BY 3-DIRECTIONAL MAGNETIC-RESONANCE VELOCITY MAPPING
HELICAL AND RETROGRADE SECONDARY FLOW PATTERNS IN THE AORTIC-ARCH STUDIED BY 3-DIRECTIONAL MAGNETIC-RESONANCE VELOCITY MAPPING
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DOI：
10.1161/01.cir.88.5.2235
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发表时间：
1993-11-01
期刊：
影响因子：
37.8
通讯作者：
LONGMORE, DB
中科院分区：
文献类型：
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作者：
KILNER, PJ;YANG, GZ;LONGMORE, DB
背景在主动脉中已记录到螺旋和逆行的次级血流，但它们的起源和与弓的关系尚不清楚。我们开始使用磁共振速度图来做这件事。方法和结果。采用三维相位对比电影磁共振速度标测技术，对10名健康志愿者的动脉进行多方向流速标测。计算机处理用于可视化所选平面中的How矢量模式。右螺旋血流在收缩晚期的主动脉弓上部占主导地位，在10名受试者中的9名中清晰可辨。随着轴向速度从峰值1.0 m/s（+/-0.1 m/s）下降，该区域的非轴向速度分量达到0.29 m/s（+/-0.05 m/s）。降主动脉上段的螺旋流模式在不同的受试者之间存在差异，显然取决于弓曲率。收缩末期逆行血流起源于低动量的血液区域，通常沿着内壁弯曲。在弯曲管状体模中的流动研究显示，当流入段定位成模拟升主动脉弯曲时，在上“弓”中出现右手螺旋流动，并且在脉动流期间，在收缩末期沿着内壁发生逆行流动。螺旋流和逆行流是健康受试者主动脉内血流的一致特征，至少部分是由于主动脉弓的弯曲和血流的脉动性造成的，它们可能与循环动力学和主动脉弓粥样硬化的发病机制有关。
Background. Helical and retrograde secondary flows have been recorded in the aorta, but their origins and movements in relation to the arch have not been clarified. We set out to do this using magnetic resonance velocity mapping.Methods and Results. Three-directional phase contrast cine magnetic resonance velocity mapping was used to map multidirectional flow velocities in the aortas of 10 healthy volunteers. Computer processing was used to visualize How vector patterns in selected planes. Right-handed helical flows predominated in the upper aortic arch in late systole, being clearly recognizable in 9 of the 10 subjects. Nonaxial components of velocity in this region reached 0.29 m/s (+/-0.05 m/s) as axial velocities declined from a peak of 1.0 m/s (+/-0.1 m/s). Helical flow patterns in the upper descending aorta varied between subjects, apparently depending on arch curvature. End-systolic retrograde flow originated from regions of blood with low momentum, usually along inner wall curvatures. Flow studies in a curved tubular phantom showed right-handed helical flow in the upper ''arch'' when the inflow section was positioned to simulate ascending aortic curvature, and retrograde How occurred along the inner wall at end systole during pulsatile flow.Conclusions. Helical and retrograde streams are consistent features of intra-aortic flow in healthy subjects that result, at least in part, from the curvature of the arch and the pulsatility of flow in it. They may have significance in relation to circulatory dynamics and the pathogenesis of atheroma in the arch.