Extraordinary Effect of Microwave Irradiation on Asymmetric Catalysis
Extraordinary Effect of Microwave Irradiation on Asymmetric Catalysis
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DOI：
10.1246/cl.2010.574
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发表时间：
2010-06-05
影响因子：
1.6
通讯作者：
Yamada, Tohru
中科院分区：
文献类型：
--
作者：
Kikuchi, Satoshi;Tsubo, Tatsuyuki;Yamada, Tohru
本文报道了微波辐射对AgBF 4-膦配合物催化联芳内酯的动态-动力学拆分开环反应的影响。采用带冷却系统的多模微波反应器，并采用光纤传感器测量精确的内部反应温度。结果表明，在与常规条件几乎相同的内温下，微波辐射加速了反应，而没有任何对映选择性的损失。
We here report the effect of microwave irradiation on the atropo-enantioselective ring-opening reaction of biaryl lactones with dynamic-kinetic resolution catalyzed by AgBF4-phosphine complexes. The multimode microwave reactor with a cooling system was employed and the fiber-optic sensor was used for measurement of the accurate internal reaction temperature. It was found that the reaction was accelerated by microwave irradiation without any loss of enantioselectivity at almost the same internal temperature as the conventional conditions.