Concepts in antibody phage display.

Concepts in antibody phage display.
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DOI:
10.1093/bfgp/1.2.189
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发表时间:
2002-07-01
期刊:
Briefings in Functional Genomics & Proteomics
影响因子:
--
通讯作者:
Jermutus, Lutz
Jermutus, Lutz
中科院分区:
其他
文献类型:
--
作者:
Carmen, Sara;Jermutus, Lutz

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本文介绍了抗体噬菌体展示及其在组合生物化学中的应用。重点是概述噬菌体展示格式,库设计和选择技术,这是成功分离针对不同靶抗原的特异性抗体片段的先决条件。
This paper introduces the reader to antibody phage display and its use in combinatorial biochemistry. The focus is on overviewing phage display formats, library design and selection technology, which are the prerequisites for the successful isolation of specific antibody fragments against a diverse set of target antigens.