Antioxidant effect of purslane (Portulaca oleracea) and its mechanism of action
Antioxidant effect of purslane (Portulaca oleracea) and its mechanism of action
复制标题
DOI：
--
复制
发表时间：
2011-05
影响因子：
--
通讯作者：
M. Dkhil;A. Moniem;S. Al-Quraishy;R. Saleh
中科院分区：
文献类型：
--
作者：
M. Dkhil;A. Moniem;S. Al-Quraishy;R. Saleh
以成年雄性废白鼠为实验动物，对马齿苋水果汁进行了抗氧化活性的筛选。通过测定还原型谷胱甘肽、过氧化氢酶、超氧化物歧化酶、谷胱甘肽还原酶、谷胱甘肽-S转移酶和谷胱甘肽过氧化物酶活性，以及对大鼠肝、肾、睾丸组织中脂质过氧化和一氧化氮的抑制作用来测定其抗氧化活性。同时测定肝、肾功能。给大鼠灌服马齿苋水汁后，所有研究参数均有显著改善。根据以上结果，马齿苋是一种很有前途的天然产物，可用于预防由氧化应激引起的心血管、神经退行性疾病和其他慢性疾病。
Aqueous juice from purslane ( Portulaca oleracea ) was screened for its antioxidant activity in adult male Waster albino rats. The antioxidant activity was determined by measuring reduced glutathione, catalase, superoxide dismutase, glutathione reductase, glutathione-S-transferase and glutathione peroxidase, as well as the inhibition in lipid peroxidation, nitric oxide in liver, kidney and testis of rats. Liver and kidney function were also determined. Administered rats with aqueous juice of purslane, resulted in marked improvement in all studied parameters. On the basis of the above results, it can be concluded that purslane is a promising natural product, which could be useful for the prevention of cardiovascular, neurodegenerative and other chronic diseases caused by oxidative stress.