Mapping quantitative trait loci regulating chicken body composition traits
Mapping quantitative trait loci regulating chicken body composition traits
复制标题
绘制调节鸡身体成分性状的数量性状位点
DOI：
10.1111/j.1365-2052.2009.01911.x
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发表时间：
2009-12-01
期刊：
影响因子：
2.4
通讯作者：
Hu, X. X.
中科院分区：
文献类型：
--
作者：
Gao, Y.;Du, Z. Q.;Hu, X. X.
对白色普利茅斯洛克鸡与丝羽乌骨鸡杂交的F-2资源群体进行了基因组扫描，以检测影响鸡体组成性状的QTL。用129个微卫星标记对来自15个全同胞家系的238个F-2个体的12个体组成性状进行了基因型和表型分析。总共发现了21个全基因组QTL，它们与11个性状有关，其中包括两个新研究的性状前胃重和胫围。其中3个QTL在全基因组范围内达到显著水平：GGA 1位于499 cm（解释表型方差的3.6%，P < 0.01），GGA 5位于51 cm（解释表型方差的3.3%，P < 0.05），GGA 1位于502 cm（解释表型方差的1.4%，P < 0.05）。GGA 1上的QTL具有多效性效应，对肌胃重、胫围和肠长的影响分别为490 cm、489 cm和481 cm。因此，对GGA 1和GGA 5两个与胫相关性状的QTL可能的多效性效应的研究还有待进一步深入。
P>Genome scans were conducted on an F-2 resource population derived from intercross of the White Plymouth Rock with the Silkies Fowl to detect QTL affecting chicken body composition traits. The population was genotyped with 129 microsatellite markers and phenotyped for 12 body composition traits on 238 F-2 individuals from 15 full-sib families. In total, 21 genome-wide QTL were found to be responsible for 11 traits, including two newly studied traits of proventriculus weight and shank girth. Three QTL were genome-wide significant: at 499 cm on GGA1 (explained 3.6% of phenotypic variance, P < 0.01) and 51 cm on GGA5 (explained 3.3% of phenotypic variance, P < 0.05) for the shank & claw weight and 502 cm on GGA1 (explained 1.4% of phenotypic variance, P < 0.05) for wing weight. The QTL on GGA1 seemed to have pleiotropic effects, also affecting gizzard weight at 490 cm, shank girth at 489 cm and intestine length at 481 cm. It is suggested that further efforts be made to understand the possible pleiotropic effects of the QTL on GGA1 and that on GGA5 for two shank-related traits.