Sex-related differences in sudomotor function in healthy early twenties focused on activated sweat gland density
Sex-related differences in sudomotor function in healthy early twenties focused on activated sweat gland density
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DOI：
10.4103/cjp.cjp_46_19
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发表时间：
2020-01-01
影响因子：
1.8
通讯作者：
Yun, Bahda
中科院分区：
文献类型：
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作者：
Park, Tae-Hwan;Lee, Jeong-Beom;Yun, Bahda
本研究的目的是通过测量皮肤表面积和活性汗腺密度(ASGD)来定量评估健康男性和女性在20岁出头时运动功能的差异。用定量运动轴突反射试验(QSART)评价自主神经系统活性。在QSART中，汗腺通过离子导入直接或间接地通过皮下应用神经递质，如乙酰胆碱来激活。这一系列机制被称为运动轴突反射。在记录了年龄、身高、体重和前臂的几项测量后，对101名21-26岁的健康对照组进行了QSART，以测量ASGD。测日平均温湿度2018年5月3日为11.4摄氏度和58.1%，2018年5月10日为14.7摄氏度和70.3%。独立样本t检验结果显示女性ASGD较高(P<；0.05)。男性的体表面积和前臂表面积较高(P<；0.001)，但激活的汗腺数量在性别上没有显著差异。男性和女性的身体和前臂的活性汗腺计数按年龄进行线性回归分析。除男性身体的活性汗腺数量外，分析显示随着年龄的增长，汗腺数量有减少的趋势，但在任何情况下都没有统计学意义(P>；0.05)。显示决定系数(R2)不足，性别和年龄的多元回归分析没有纠正年龄和激活汗腺数量之间的这种不显著。
The purpose of this study was to quantitatively assess the difference in sudomotor function between healthy males and females in their early twenties by measuring skin surface area and activated sweat gland density (ASGD). The quantitative sudomotor axon reflex test (QSART), a method for evaluating autonomic nervous system activity, was used for quantification. In QSART, the sweat glands are activated directly or indirectly by the subcutaneous application of neurotransmitters, such as acetylcholine, through iontophoresis. This series of mechanisms is called the sudomotor axon reflex. After recording age, height, weight, and several measurements of the forearm, QSART was performed on 101 healthy controls aged 21-26 years to measure ASGD. The mean temperature and humidity on the measurement days were 11.4 degrees C and 58.1% on May 3, 2018, and 14.7 degrees C and 70.3% on May 10, 2018. The result of independent sample t-test showed higher ASGD in women (P < 0.05). The body surface area and the surface area of the forearms were higher in men (P < 0.001), but the number of activated sweat glands was not significantly different according to sex. The activated sweat gland counts of the body and forearms were analyzed through linear regression by age for males and females. Except for the activated sweat gland count of the male body, the analysis showed a tendency to decrease with increasing age but was not statistically significant in any case (P > 0.05). Showing insufficient coefficient of determination (R2), multiple regression analyses with sex and ages did not correct this insignificance between age and activated sweat gland count.