Quantification of an oval optic disc in relation to myopic foveoschisis using swept-source optical coherence tomography.
Quantification of an oval optic disc in relation to myopic foveoschisis using swept-source optical coherence tomography.
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DOI：
10.1186/s12886-022-02319-9
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发表时间：
2022-02-22
影响因子：
2
通讯作者：
Chen H
中科院分区：
文献类型：
--
作者：
Zhu K;Lei B;Wang K;Song F;Jiang R;Chang Q;Xu G;Chen H
利用扫频光源光学相干断层扫描（SS-OCT）研究椭圆形视盘与近视性黄斑裂孔（MF）发生的关系。25例单侧MF患者的50只眼被纳入这项回顾性观察性研究。采用SS-OCT评价视盘和视乳头周围结构的生物计量学特征，MF眼的视盘椭圆度指数（OI）显著小于对侧眼（P = 0.003），视盘倾斜角显著大于对侧眼（P = 0.023）。视盘倾斜角与OI显著相关（P = 0.000）。广义估计方程（GEE）模型（线性回归）显示等效球镜（P = 0.001）、黄斑葡萄肿狭窄（P = 0.001）和MF的发生（P = 0.026）是影响OI的独立因素。MF患者的黄斑葡萄肿较窄（P = 0.020），葡萄肿较深（P = 0.006）。GEE模型（Logistic回归）显示，狭窄的黄斑葡萄肿是唯一与MF发生相关的独立因素（P = 0.013）。MF患者的视盘呈椭圆形，这是由于围绕垂直盘轴的倾斜度增加所致。视盘倾斜与狭窄性黄斑葡萄肿有关，是唯一与MF发生相关的独立因素。临床相关性需要通过纵向分析进一步探索。在线版本包含补充材料，可通过10.1186/s12886-022-02319-9获得。
To investigate the relationship between an oval optic disc and the occurrence of myopic foveoschisis (MF) using swept-source optic coherence tomography (SS-OCT). Fifty eyes of 25 patients with unilateral MF were included in this retrospective observational study. The biometric features of the optic disc and peripapillary structures were evaluated using SS-OCT. The ovality index (OI) of the optic disc was significantly smaller (P = 0.003) and the optic disc tilt angle was greater (P = 0.023) in the eyes with MF than in the contralateral eyes. The optic disc tilt angle was significantly correlated with the OI (P = 0.000). Generalized estimating equation (GEE) model (linear regression) demonstrated that spherical equivalent refraction (P = 0.001), narrow macular staphyloma (P = 0.001) and the occurrence of MF (P = 0.026) were the independent factors associated with the OI. Narrow macular staphyloma was more frequent (P = 0.020) and the staphyloma was deeper (P = 0.006) in eyes with MF. GEE model (logistic regression) revealed that narrow macular staphyloma was the only independent factor related to the occurrence of MF (P = 0.013). An oval optic disc in eyes with MF resulted from the increased tilt around the vertical disc axis. The optic disc tilt was related to narrow macular staphyloma, which was the only independent factor associated with the occurrence of MF. The clinical relevance needs further exploration through longitudinal analysis. The online version contains supplementary material available at 10.1186/s12886-022-02319-9.
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影响因子：
13.7
作者：
Shimada, Noriaki;Ohno-Matsui, Kyoko;Mochizuki, Manabu
通讯作者：
Mochizuki, Manabu
影响因子：
13.7
作者：
Park, Hae-Young L.;Lee, Kook;Park, Chan Kee
通讯作者：
Park, Chan Kee
影响因子：
4.2
作者：
Tay, E;Seah, SK;Aung, T
通讯作者：
Aung, T
DOI：
10.1097/iae.0000000000000358
发表时间：
2015-04-01
影响因子：
3.3
作者：
Dai, Yi;Jonas, Jost B.;Sun, Xinghuai
通讯作者：
Sun, Xinghuai
影响因子：
13.7
作者：
Shinohara, Kosei;Tanaka, Noriko;Ohno-Matsui, Kyoko
通讯作者：
Ohno-Matsui, Kyoko