Cardioprotective effects of vegetables:: Is nitrate the answer?
Cardioprotective effects of vegetables:: Is nitrate the answer?
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DOI：
10.1016/j.niox.2006.01.013
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发表时间：
2006-12-01
影响因子：
3.9
通讯作者：
Weitzberg, Eddie
中科院分区：
文献类型：
--
作者：
Lundberg, Jon O.;Feelisch, Martin;Weitzberg, Eddie
富含水果和蔬菜的饮食与某些形式的癌症和心血管疾病的风险降低有关，但这种保护背后的机制尚未完全了解。最近的流行病学研究表明，绿色多叶蔬菜特别具有心脏保护作用。我们在这里提出，这些有益的效果与高含量的无机硝酸盐有关，无机硝酸盐与口腔中的共生细菌一起转化为亚硝酸盐，一氧化氮和具有血管扩张和组织保护特性的次级反应产物。(c)2006爱思唯尔公司All rights reserved.
A diet rich in fruits and vegetables is associated with a lower risk of certain forms of cancer and cardiovascular disease, but the mechanisms behind this protection are not completely understood. Recent epidemiological studies suggest a cardioprotective action afforded specifically by green leafy vegetables. We here propose that these beneficial effects are related to the high content of inorganic nitrate, which in concert with symbiotic bacteria in the oral cavity is converted into nitrite, nitric oxide, and secondary reaction products with vasodilating and tissue-protective properties. (c) 2006 Elsevier Inc. All rights reserved.