Seasons of Risk: Anticipated Behavior on Vacation and Interest in Episodic Antiretroviral Pre-exposure Prophylaxis (PrEP) Among a Large National Sample of U.S. Men Who have Sex with Men (MSM).
Seasons of Risk: Anticipated Behavior on Vacation and Interest in Episodic Antiretroviral Pre-exposure Prophylaxis (PrEP) Among a Large National Sample of U.S. Men Who have Sex with Men (MSM).
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DOI：
10.1007/s10461-015-1238-0
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发表时间：
2016-07
影响因子：
4.4
通讯作者：
Mayer KH
中科院分区：
文献类型：
--
作者：
Elsesser SA;Oldenburg CE;Biello KB;Mimiaga MJ;Safren SA;Egan JE;Novak DS;Krakower DS;Stall R;Mayer KH
目前的分析评估了在预期风险增加的短期发作（即Epi-PrEP）期间每日PrEP的兴趣和可接受性。2013年，一个基于互联网的MSM性网络网站的美国成员被邀请完成一项关于度假背景下艾滋病毒预防做法的调查。7，305名男男性行为者回答了调查。在过去一年度假的受访者中，25.6%的人报告在度假时与新的男性性伴侣进行了无套肛交（CAS）。大多数（92.6%）受访者认为，必须每天使用PrEP是使用PrEP的障碍，74.3%的受访者表示，如果他们知道PrEP对预期风险增加的短期内有帮助，他们会采取PrEP。在过去的一年中，在度假期间报告CAS增加的MSM更有可能表示，如果在短期内使用PrEP有帮助，他们将比没有的受访者更愿意服用PrEP（aOR=2.02，95%CI 1.59-2.56，p <0.001）。旨在评估短期PrEP课程的吸收，坚持和保护益处的研究是必要的。
The current analysis evaluates interest in and acceptability of daily PrEP during short episodes of anticipated increased risk (i.e. Epi-PrEP). In 2013, U.S. members of an Internet-based MSM sexual networking site were invited to complete a survey about HIV prevention practices in the context of vacationing. 7,305 MSM responded to the survey. Of respondents who had vacationed in the past year, 25.6% reported condomless anal sex (CAS) with new male sex partners while vacationing. Most (92.6%) respondents agreed that having to use PrEP every day was a barrier to PrEP use and 74.3% indicated they would take PrEP if they knew it would be helpful for short periods of anticipated increased risk. MSM who reported increased CAS while on vacation in the past year were more likely to indicate that they would take PrEP if it were helpful when used for short periods than respondents who did not (aOR=2.02, 95% CI 1.59–2.56, p <0.001). Studies designed to evaluate uptake, adherence, and protective benefit of short PrEP courses are warranted.