Surgical treatment of intractable epilepsy originating from the primary sensory area of the hand - Case report

Surgical treatment of intractable epilepsy originating from the primary sensory area of the hand - Case report
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DOI:
10.2176/nmc.39.246
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发表时间:
1999-03-01
影响因子:
1.9
通讯作者:
Yoshimoto, T
Yoshimoto, T
中科院分区:
医学4区
文献类型:
--
作者:
Asano, E;Ishikawa, S;Yoshimoto, T

文献摘要

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一个14岁的右撇子女孩提出顽固性癫痫起源于手的初级感觉区,表现为感觉部分癫痫发作在左手与继发泛化。神经学检查未见异常,磁共振成像、脑磁图和慢性硬膜下电极皮质刺激显示位于手部初级感觉皮层的病变,其中通过24小时颅内脑电图记录确定了发作区。手术切除病变并对相邻皮质进行多次枕下横切。组织学诊断为胚胎发育异常神经上皮瘤(DNT)。术后完全无癫痫发作,无永久性感觉缺陷。如果进行准确的功能定位和手术切除,位于主要感觉手区的DNT可以切除而不会造成术后感觉缺陷。
A 14-year-old right-handed girl presented with intractable epilepsy originating from the primary sensory area of the hand, manifesting as sensory partial seizures in the left hand with secondary generalization. Neurological examination showed no abnormal findings, Magnetic resonance imaging, magnetoencephalography, and cortical stimulation using chronic subdural electrodes demonstrated a lesion located in the primary sensory cortex of the hand, in which the ictal onset zone was identified by 24-hour intracranial electroencephalographic recording. Surgical resection of the lesion and multiple subpial transections of the adjacent cortices were performed. The histological diagnosis was dysembryoplastic neuroepithelial tumor (DNT). She was completely free of seizures without permanent sensory deficits postoperatively. DNT located in the primary sensory hand area may be resectable without causing postoperative sensory deficits, if accurate functional mapping and surgical resection are performed.