Extreme thermal sensitivity and pain-induced sensitization in a fibromyalgia patient.
Extreme thermal sensitivity and pain-induced sensitization in a fibromyalgia patient.
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纤维肌痛患者的极度热敏感性和疼痛引起的敏化。
DOI：
10.1155/2010/912513
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发表时间：
2010
影响因子：
--
通讯作者：
Mauderli,AndreP
中科院分区：
文献类型：
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作者：
Wong,Fong;Rodrigues,Anthony;Schmidt,Siegfried;VierckJr,CharlesJ;Mauderli,AndreP
在纤维肌痛综合征（FMS）的心理物理学研究过程中，一名长期头痛和面部疼痛的受试者表现出异常严重的热异常性疼痛。她对皮肤热痛评级的刺激反应函数显示其敏感性明显超出正常对照和大多数 FMS 受试者。特别设计的心理物理学方法表明，热敏感性有时会在一系列刺激下急剧增加。先前暴露于中度热痛可触发一系列正常中性热刺激的异常疼痛评级。这些观察结果记录了一个突破性疼痛敏感性的案例，并对 FMS 疼痛机制产生影响。
During the course of a psychophysical study of fibromyalgia syndrome (FMS), one of the subjects with a long history of headache and facial pain displayed an extraordinarily severe thermal allodynia. Her stimulus‐response function for ratings of cutaneous heat pain revealed a sensitivity clearly beyond that of normal controls and most FMS subjects. Specially designed psychophysical methods showed that heat sensitivity sometimes increased dramatically within a series of stimuli. Prior exposure to moderate heat pain served as a trigger for allodynic ratings of series of normally neutral thermal stimulation. These observations document a case of breakthrough pain sensitivity with implications for mechanisms of FMS pain.