Effects of dipping and psychological traits on morning surge in blood pressure in healthy people.
Effects of dipping and psychological traits on morning surge in blood pressure in healthy people.
复制标题
浸渍和心理特征对健康人早晨血压升高的影响。
DOI：
10.1038/jhh.2011.34
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发表时间：
2012
影响因子：
2.7
通讯作者：
Shapiro,D
中科院分区：
文献类型：
--
作者：
FitzGerald,L;Ottaviani,C;Goldstein,IB;Shapiro,D
尽管焦虑、抑郁和敌意在心血管疾病的发病机制中发挥着重要作用，但它们对两个重要的心血管危险因素——夜间血压下降和早晨血压升高（MSBP）——的影响却在很大程度上被忽视，并且主要在临床人群中进行研究。本研究探讨了浸渍和心理特征对健康人群 MSBP 的影响。夜间血压和 MSBP 源自 77 名男性和 79 名女性的 24 小时动态血压，平均年龄 32.8 岁（标准差：7.4）。通过问卷调查研究了抑郁、焦虑和敌意的差异。较高水平的低沉（P < 0.0001）和抑郁症状（P = 0.01）独立地导致MSBP增加。在确定 MSBP 时，情绪低落与抑郁（P=0.04）、敌意（P=0.01）和焦虑（P=0.04）相互作用。心理特征得分较高的低北斗者的 MSBP 高于高北斗者。性别与抑郁症状 (P = 0.05)、焦虑 (P < 0.0001) 和敌意 (P = 0.01) 之间存在显着的 MSBP 交互作用，男性中观察到的分数越高，MSBP 越高。研究结果强调抑郁症是 MSBP 的预测因子，与下降无关。浸渍和非浸渍模式、心理特征和 MSBP 之间的临床显着关系需要进一步研究。
Despite the role of anxiety, depression and hostility in the pathogenesis of cardiovascular diseases, their impact on two significant cardiovascular risk factors, nocturnal dipping and morning surge in blood pressure (MSBP), are largely ignored and primarily studied in clinical populations. This study examined the effects of dipping and psychological traits on MSBP in healthy people. Nocturnal dipping and MSBP were derived from 24-h ambulatory BP obtained in 77 men and 79 women, mean age 32.8 (sd: 7.4). Differences in depression, anxiety and hostility were examined by questionnaires. Higher levels of dipping (P< 0.0001) and depressive symptoms (P= 0.01) independently contributed to increased MSBP. Dipping interacts with depression (P= 0.04), hostility (P= 0.01) and anxiety (P= 0.04) in determining MSBP. Low dippers with higher scores on the psychological traits showed higher MSBP than high dippers. A significant MSBP interaction was found between sex and depressive symptoms (P= 0.05), anxiety (P< 0.0001) and hostility (P= 0.01) with higher scores associated with increased MSBP observed in males. Findings underscore depression as a predictor of MSBP independent of dipping. The clinically significant relationship between dipping and non-dipping patters, psychological traits and MSBP requires further investigation.