Communication theory aspects of synaptic transmission
Communication theory aspects of synaptic transmission
复制标题
突触传递的通讯理论方面
DOI：
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
I. Balasingham
中科院分区：
文献类型：
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作者：
M. Veletić;F. Mesiti;P. Floor;I. Balasingham
生物结构通常基于分子通信系统，其使用无数种分子类型来编码信息。在生物体中发现的细胞中，相互连接的神经元通过神经递质进行交流，神经递质是充当信息物理载体的粒子。由于纳米尺度组件之间的信息传播，神经元通信最近被确定为纳米网络的潜在候选者。本文阐述了神经元间分子突触传递的概念，旨在从细胞生理学的角度对物理端到端模型的性能进行分析。突触传递从几个方面进行了研究：发射器（突触前终端），通道（突触间隙），和接收器（突触后终端），其目标是表征神经元之间的尖峰速率函数的传播。此外，一些想法，如何将星形胶质细胞的过程的影响，神经元通信。
Biological structures are typically based on molecular communication systems which use a myriad of molecule types to encode messages. Among the cells found in living organisms, interconnected neurons communicate by means of neurotransmitters, particles that serve as physical carriers of information. Owing to information propagation among the nano-scale components, neuronal communication is recently identified as a potential candidate for nano-networking. This paper elaborates on the concept of molecular synaptic transmission between neurons, aiming to give an insight into the performance of physical end-to-end model according to the cell physiology. The synaptic transmission is investigated from several aspects: the transmitter (pre-synaptic terminal), the channel (synaptic cleft), and the receiver (post-synaptic terminal), with a goal to characterize the propagation of the spiking rate function between neurons. Moreover, some ideas on how to incorporate the impact of astrocytic processes to the neuronal communication are presented.