Antioxidant, mutagenic, and antimutagenic activity of frozen fruits
Antioxidant, mutagenic, and antimutagenic activity of frozen fruits
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DOI：
10.1089/jmf.2007.598
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发表时间：
2008-01-01
影响因子：
2.4
通讯作者：
Salvador, Mirian
中科院分区：
文献类型：
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作者：
Spada, Patricia D. S.;Nunes de Souza, Gabrielle Gianna;Salvador, Mirian
许多研究集中在新鲜水果对患癌症和其他与活性物质和自由基有关的疾病的风险的影响。在过去的几年里，冷冻水果的摄入量得到了广泛的推广，但到目前为止，人们还不完全了解它们的生物活性。本研究分析了23个冷冻水果样品的营养成分、总多酚、总胡萝卜素和维生素C含量。还评估了抗氧化剂、诱变剂和抗突变剂的效果。抗氧化性测定包括2，2-二苯基-1-苦基肼自由基(DPPH中心点)清除活性、超氧化物歧化酶(SOD)和过氧化氢酶(CAT)样活性的测定。对酿酒酵母真核细胞进行了诱变和抗突变实验。在DPPH中心斑点分析中，大多数样品(74%)显示出与维生素C相似的抗氧化活性，且这种活性呈正相关(r=0.366；P
Many studies have focused on the effect of fresh fruits on the risk of developing cancer and other diseases involved with reactive species and free radicals. The intake of frozen fruits has spread widely in the last years, but, until now, their biological activity is not completely known. In this study, 23 samples of frozen fruits were analyzed for their nutritional composition, total polyphenols, total carotenoids, and vitamin C content. Antioxidant, mutagenic, and antimutagenic effects were also evaluated. Antioxidant assays included 2,2-diphenyl-1-picrylhydrazyl radical (DPPH center dot) scavenging activity and determination of superoxide dismutase (SOD)- and catalase (CAT)-like activities. Mutagenic and antimutagenic evaluations were performed in eukaryotic cells of Saccharomyces cerevisiae yeast. Most samples (74%) showed antioxidant activity similar to vitamin C in the DPPH center dot assay, and this activity was positively correlated (r = 0.366; P