From mice to men. Commonalities in physiology for stem cell-based cardiac repair.

From mice to men. Commonalities in physiology for stem cell-based cardiac repair.
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DOI:
10.1016/j.jacc.2009.06.054
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发表时间:
2009-12
影响因子:
24
通讯作者:
Marc S. Penn;S. Anwaruddin;Ravi Nair;Stephen G. Ellis
Marc S. Penn;S. Anwaruddin;Ravi Nair;Stephen G. Ellis
中科院分区:
医学1区
文献类型:
--
作者:
Marc S. Penn;S. Anwaruddin;Ravi Nair;Stephen G. Ellis

文献摘要

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目前急性心肌梗死(AMI)的治疗包括通过经皮方法或纤溶治疗成功恢复梗死相关动脉的血流,已显示出降低短期死亡率的益处。虽然这些再灌注策略的优点是公认的,但它们不能解决心肌损失和发生的不良重塑。
Current treatments for acute myocardial infarction (AMI) involving successful restoration of blood flow into the infarct-related artery either by percutaneous methods or by fibrinolytic therapy have shown to be of benefit in reduction of short-term mortality. While the advantages of these reperfusion strategies are well established, they do not address the loss of myocardium and adverse remodeling that occurs.