Cancer in sub-Saharan Africa: a Lancet Oncology Commission.
Cancer in sub-Saharan Africa: a Lancet Oncology Commission.
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DOI：
10.1016/s1470-2045(21)00720-8
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发表时间：
2022-06
期刊：
影响因子：
51.1
通讯作者：
Kerr, David
中科院分区：
文献类型：
--
作者：
Ngwa, Wilfred;Addai, Beatrice W.;Adewole, Isaac;Ainsworth, Victoria;Alaro, James;Alatise, Olusegun, I;Ali, Zipporah;Anderson, Benjamin O.;Anorlu, Rose;Avery, Stephen;Barango, Prebo;Bih, Noella;Booth, Christopher M.;Brawley, Otis W.;Dangou, Jean-Marie;Denny, Lynette;Dent, Jennifer;Elmore, Shekinah N. C.;Elzawawy, Ahmed;Gashumba, Diane;Geel, Jennifer;Graef, Katy;Gupta, Sumit;Gueye, Serigne-Magueye;Hammad, Nazik;Hessissen, Laila;Ilbawi, Andre M.;Kambugu, Joyce;Kozlakidis, Zisis;Manga, Simon;Maree, Lize;Mohammed, Sulma, I;Msadabwe, Susan;Mutebi, Miriam;Nakaganda, Annet;Ndlovu, Ntokozo;Ndoh, Kingsley;Ndumbalo, Jerry;Ngoma, Mamsau;Ngoma, Twalib;Ntizimira, Christian;Rebbeck, Timothy R.;Renner, Lorna;Romanoff, Anya;Rubagumya, Fidel;Sayed, Shahin;Sud, Shivani;Simonds, Hannah;Sullivan, Richard;Swanson, William;Vanderpuye, Verna;Wiafe, Boateng;Kerr, David
在撒哈拉以南非洲，需要采取紧急行动，遏制日益严重的癌症发病率和死亡率危机。如果不采取快速干预措施，数据估计显示，癌症死亡率将从2020年的520348人大幅增加到2030年的每年约100万人。在这里，我们详细介绍了撒哈拉以南非洲的癌症状况，在分析的基础上提出了关键行动建议，并强调了案例研究和成功的模式，这些模式可以在整个地区进行模仿、调整或改进，以减少日益严重的癌症危机。建议采取的行动开始是需要在每个国家制定或更新国家癌症控制计划。计划必须包括儿童癌症计划，管理艾滋病毒和营养不良等合并症，可靠和可预测的药物供应，以及提供心理社会，支持和姑息治疗。计划还应包括80%以上的SSA人口采用的传统，补充和替代医疗实践，以及减少漏诊和延迟转诊的途径。需要更多的投资来发展癌症登记和核心癌症检测的癌症诊断。我们发现，对COVID-19大流行期间使用的一些方法（如大分割放射治疗和远程医疗）的投资和更多采用，可以大幅增加非洲获得癌症护理的机会，加速癌症预防和控制工作，提高生存率，并在未来十年节省数十亿美元。非洲第一夫人参与癌症预防工作是一种切实可行的做法，应在整个撒南非洲推广。此外，对劳动力培训的投资对于到2030年防止数百万可避免的死亡至关重要。我们提出了一个框架，可用于战略规划癌症研究增强SSA，在研究投资，可以产生投资回报，并有助于推动政策和有效的合作。扩大全民健康覆盖范围，将癌症纳入基本福利计划也至关重要。实施委员会建议的行动对于减少撒哈拉以南非洲日益严重的癌症危机和实现对联合国可持续发展目标的政治承诺至关重要，该目标是到2030年将非传染性疾病的过早死亡率降低三分之一。
In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in cancer incidence and mortality. Without rapid interventions, data estimates show a major increase in cancer mortality from 520 348 in 2020 to about 1 million deaths per year by 2030. Here, we detail the state of cancer in SSA, recommend key actions on the basis of analysis, and highlight case studies and successful models that can be emulated, adapted, or improved across the region to reduce the growing cancer crises. Recommended actions begin with the need to develop or update national cancer control plans in each country. Plans must include childhood cancer plans, managing comorbidities such as HIV and malnutrition, a reliable and predictable supply of medication, and the provision of psychosocial, supportive, and palliative care. Plans should also engage traditional, complementary, and alternative medical practices employed by more than 80% of SSA populations and pathways to reduce missed diagnoses and late referrals. More substantial investment is needed in developing cancer registries and cancer diagnostics for core cancer tests. We show that investments in, and increased adoption of, some approaches used during the COVID-19 pandemic, such as hypofractionated radiotherapy and telehealth, can substantially increase access to cancer care in Africa, accelerate cancer prevention and control efforts, increase survival, and save billions of US dollars over the next decade. The involvement of African First Ladies in cancer prevention efforts represents one practical approach that should be amplified across SSA. Moreover, investments in workforce training are crucial to prevent millions of avoidable deaths by 2030. We present a framework that can be used to strategically plan cancer research enhancement in SSA, with investments in research that can produce a return on investment and help drive policy and effective collaborations. Expansion of universal health coverage to incorporate cancer into essential benefits packages is also vital. Implementation of the recommended actions in this Commission will be crucial for reducing the growing cancer crises in SSA and achieving political commitments to the UN Sustainable Development Goals to reduce premature mortality from non-communicable diseases by a third by 2030.
影响因子：
1.8
作者：
Asana L;Irabor C;Seppo S;Jean C;Ngoma T;Elzawawy A;Ngwa W
通讯作者：
Ngwa W
影响因子：
1.8
作者：
Chofor N;Bopda P;Bücker R;Ivo A;Okonkwo E;Joel K;Tung Z;Ige T;Wirtz H;Ngwa W
通讯作者：
Ngwa W