Crossing fiber arrays in the rat hippocampus as demonstrated by three‐dimensional reconstruction
Crossing fiber arrays in the rat hippocampus as demonstrated by three‐dimensional reconstruction
复制标题
三维重建证明大鼠海马中的交叉纤维阵列
DOI：
10.1002/cne.903030309
复制
发表时间：
1991
影响因子：
2.5
通讯作者：
Y. Nojyo
中科院分区：
文献类型：
--
作者：
N. Tamamaki;Y. Nojyo
海马体是在短期记忆中发挥关键作用的神经基质。为了更好地了解海马在“学习和记忆”中的功能，我们对 CA3 锥体神经元和齿状筋膜颗粒细胞进行了细胞内辣根过氧化物酶 (HRP) 研究。 CA3 锥体神经元的轴突有两个组成部分：纵向关联系统和谢弗侧支系统。后一成分以层状方式组织并遵循肺纤维流。对有髓纤维的电子显微镜分析表明，海马中的大多数有髓纤维与肺纤维平行排列。然而，颗粒细胞的苔藓纤维并不遵循肺纤维流。我们提出了一种大鼠海马固有兴奋回路组织的新模型，其中锥体细胞和颗粒细胞的独特层状组织创建了一个交叉神经网络。
The hippocampus is a neural substrate playing a key role in short‐term memory. In order to achieve a better understand‐ding of how the hippocampus functions in “learning and memory,” we conducted an intracellular horseradish peroxidase (HRP) study of the CA3 pyramidal neurons and the granule cells of the fascia dentata. The axon of the CA3 pyramidal neurons has two components, the longitudinal association system and the Schaffer collateral system. The latter component is organized in a lamellar fashion and follows the alvear fiber stream. An electron microscopic analysis of myelinated fibers suggested that most myelinated fibers in the hippocampus are organized parallel to the alvear fibers. The mossy fibers of the granule cells, however, do not follow the alvear fiber stream. We propose a new model of the organization of the intrinsic excitatory circuitry of the rat hippocampus in which the distinct lamellar organization of the pyramidal and granule cells creates a crossing neural network.