SEVERE PREECLAMPSIA-ECLAMPSIA IN YOUNG PRIMIGRAVID WOMEN - SUBSEQUENT PREGNANCY OUTCOME AND REMOTE PROGNOSIS
SEVERE PREECLAMPSIA-ECLAMPSIA IN YOUNG PRIMIGRAVID WOMEN - SUBSEQUENT PREGNANCY OUTCOME AND REMOTE PROGNOSIS
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DOI：
10.1016/0002-9378(86)90336-4
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发表时间：
1986-11-01
影响因子：
9.8
通讯作者：
GONZALEZRUIZ, A
中科院分区：
文献类型：
--
作者：
SIBAI, BM;ELNAZER, A;GONZALEZRUIZ, A
The purpose of this report is to compare subsequent outcome and incidence of chronic hypertension and diabetes on follow-up in two groups of patients. Group 1 included 406 young women who had severe preeclampsia-eclampsia in their first pregnancies. Group 2 consisted of 409 young, well-matched women who remained normotensive during their first pregnancies. All patients were followed up for a minimum of 2 years (range 2 to 24). The preeclamptic-eclamptic group had a higher incidence of preeclampsia in their second pregnancies (46.8% versus 7.6%, p < 0.001) and in subsequent pregnancies (20.7% versus 7.7%, p < 0.001) when compared with the normotensive group. The overall incidence of chronic hypertension was significantly higher in the preeclamptic-eclamptic group (14.8% versus 5.6%, p < 0.001). Most of the difference occurred in patients followed up .gtoreq. 10 years. Within the preeclamptic-eclamptic group, patients having preeclampsia-eclampsia at .ltoreq. 30 weeks'' gestation and those having recurrent preeclampsia in their second pregnancies had a significantly higher incidence of subsequent chronic hypertension (p < 0.001) than was found in the other patients. Within the normotensive group, patients remaining normotensive in subsequent pregnancies had the lowest incidence of chronic hypertension (1.8%).
