Effects of nitroglycerin and dipyridamole on acute myocardial infarction: a thermographic study in the dog.

Effects of nitroglycerin and dipyridamole on acute myocardial infarction: a thermographic study in the dog.
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硝酸甘油和双嘧达莫对急性心肌梗死的影响:狗的热成像研究。

DOI:
10.1093/cvr/13.5.281
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发表时间:
1979
影响因子:
10.8
通讯作者:
S. Bornmyr
S. Bornmyr
中科院分区:
医学1区
文献类型:
--
作者:
A. Malm;M. Arborelius;Bo Lilja;Ramon Lillo Gil;S. Bornmyr

文献摘要

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用热像技术研究了等剂量硝酸甘油和潘生丁降压对开胸犬急性心肌梗死的影响。硝酸甘油并不能减少九只狗中任何一只的冷血缺血区。在6只可以正确测量缺血区的狗身上,凉爽的区域略有增大。在所有使用的20只狗中,潘生丁缩小了缺血区的面积。在19个大小可以充分数字化的患者中,梗死面积的减少在统计学上是显著的。
The effects on an acute myocardial infarction of equipotent hypotensive doses of nitroglycerin and dipyridamole were studied using the thermographic technique in open-chest dogs. Nitroglycerin did not reduce the cool ischaemic area in any of the nine dogs studied. In six of the dogs, in which the ischaemic region could be properly measured, the cool area slightly grew in size. Dipyridamole reduced the size of the ischaemic area in all the 20 dogs used. In the 19 in which the size could be adequately digitalised, the decrease in infarction size was statistically significant.