A novel putative neuropeptide receptor expressed in neural tissue, including sensory epithelia.
A novel putative neuropeptide receptor expressed in neural tissue, including sensory epithelia.
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一种新型推定神经肽受体，在神经组织（包括感觉上皮）中表达。
DOI：
10.1006/bbrc.1995.1563
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Thompson,DA
中科院分区：
文献类型：
--
作者：
Tal,M;Ammar,DA;Karpuj,M;Krizhanovsky,V;Naim,M;Thompson,DA
我们已经使用了同源性为基础的方法，以确定优先在视网膜和味觉细胞中表达的G蛋白偶联受体。大鼠和牛的序列编码一种新的G蛋白偶联受体已被分离。分析表明，虽然蛋白质序列与生长抑素和阿片类药物的受体最相似，但它不太可能是这些受体的亚型。北方和RNA酶保护分析表明该基因优先在神经和感觉组织中表达。
We have used a homology based approach to identify G protein-coupled receptors preferentially expressed in retinal and taste cells. Rat and bovine sequences encoding a novel G protein-coupled receptor have been isolated. Analysis indicates that while the protein sequence is most similar to the receptors for somatostatin and opiates, it is unlikely to be a subtype of these receptors. Northern and RNase protection analysis indicates that the gene is preferentially expressed in neural and sensory tissues.