JUNCTIONS BETWEEN FIBROBLASTS IN MOUSE PERIODONTAL-LIGAMENT
JUNCTIONS BETWEEN FIBROBLASTS IN MOUSE PERIODONTAL-LIGAMENT
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DOI：
10.1111/j.1600-0765.1980.tb00326.x
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发表时间：
1980-01-01
影响因子：
3.5
通讯作者：
EVERTS, V
中科院分区：
文献类型：
--
作者：
BEERTSEN, W;EVERTS, V
对小鼠切牙和磨牙牙周膜成纤维细胞间细胞间连接的分布进行了定量评价，结果表明，牙侧的细胞间隙连接结构明显多于骨侧。这种差异在不断萌出的门牙的韧带上尤为明显。这里，类间隙结结构的数密度估计为.apprx。牙骨质邻近结缔组织中成纤维细胞20例，牙槽骨组织中成纤维细胞4例。在粘附型连接的分布方面，切牙和磨牙韧带的不同区域之间的差异较小。对于切牙，粘附型连接在与牙齿相关的牙室中平均为30个/细胞，在牙槽骨中为20个/细胞。在磨牙中，细胞间连接贯穿整个韧带；在切牙中，细胞间连接局限于两个主要的结缔组织间，即牙侧与萌牙沿口腔方向移动的一侧和相对于牙槽壁保持不动的骨侧的一侧。在后两个隔室之间的过渡区，交界处非常稀疏。小鼠牙周膜成纤维细胞间连接的分布模式可能反映了组织中不同区域细胞之间的功能差异；这种差异可能与细胞运动和胶原代谢的过程有关。
Quantitative evaluation of the distribution of intercellular junctions between fibroblasts in the incisor and molar periodontal ligament of the mouse indicated that the structures resembling gap junctions are apparently more frequent on the tooth side of this tissue than on the bone side. The difference was particularly evident for the ligament of the continuously erupting incisor. Here, the numerical density of gap junction-like structures was estimated to be .apprx. 20/fibroblast in the connective tissue adjacent to the cementum and 4/fibroblast in the tissue along the alveolar bone. With regard to the distribution of adherens-type junctions, less variation was observed between the various zones of the incisor and molar ligament. For the incisor, the average number of adherens-type junctions was in the order of 30 junctions/cell in the tooth-related compartment and 20 junctions/cell in the alveolar compartment. Although in the molar, intercellular junctions were observed throughout the entire width of the ligament; in the incisor they were confined to the 2 main connective tissue compartments, i.e., the one of the tooth side which moves with the erupting tooth in the direction of the oral cavity and the one of the bone side which remains stationary with respect to the alveolar wall. In the transitional area between the 2 latter compartments, junctions were very sparse. The distribution pattern of intercellular junctions between fibroblasts in mouse periodontal ligament probably reflects functional differences among the cells in the various regions of the tissue; differences that are possibly related to processes involving the movement of cells and the metabolism of collagen.