The myometrium and uterine cervix in normal and preterm labor.
The myometrium and uterine cervix in normal and preterm labor.
复制标题
正常和早产中的子宫肌层和子宫颈。
DOI：
10.1056/nejm198408303110905
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Naftolin,F
中科院分区：
文献类型：
--
作者：
Huszar,G;Naftolin,F
早产仍然是围产期发病和死亡的最重要原因。在这篇文章中，我们回顾了我们目前对子宫肌层和子宫颈的生物化学和生理学的理解，特别是因为它们与早产的发病机制和治疗有关。在怀孕期间，子宫肌层放松以适应发育中的婴儿和怀孕产物，在怀孕结束时，它提供有节奏的紧张性分娩收缩，促进子宫内容物的排出。和所有肌肉组织一样，肌层的收缩性是基于收缩蛋白肌动蛋白和肌凝蛋白的相互作用。很多，如果不是的话……
PRETERM labor remains the most important cause of perinatal morbidity and mortality. In this article we review our present understanding of the biochemistry and physiology of the myometrium and uterine cervix, particularly as they relate to the pathogenesis and therapy of preterm labor.During pregnancy, the myometrium relaxes to accommodate the developing infant and products of conception, and at the end of pregnancy, it provides the rhythmic tonic contractions of labor that facilitate expulsion of the uterine contents. As in all muscle tissue, myometrial contractility is based on the interaction of the contractile proteins actin and myosin. Many, if not . . .