Tactile detection of a dot on a smooth surface: peripheral neural events.
Tactile detection of a dot on a smooth surface: peripheral neural events.
复制标题
光滑表面上的点的触觉检测：周围神经事件。
DOI：
10.1152/jn.1986.56.4.1109
复制
发表时间：
1986
影响因子：
2.5
通讯作者：
Whitehouse,J
中科院分区：
文献类型：
--
作者：
LaMotte,RH;Whitehouse,J
通过在被动指垫上以不同的速度触摸不同高度的点，确定了人类在光滑的平板上发现单个直径550微米的隆起点的存在，并判断诱发感觉的程度的能力。麻醉猕猴指垫的机械感受性外周神经纤维分别为慢适应(SA)、快适应(RA)和机械适应(PC)纤维，记录到对相同刺激的诱发反应。当敲击速度为10 mm/S时，由检测灵敏度测量确定的所有人类观察者的点高度检测阈值在1至3微米之间。从猴子的纤维记录来看，RAS的点高度阈值为2-4微米，即在人类检测阈值的范围内。SAS的网点高度阈值为8微米或更大，PC的网点高度阈值为21微米或更大。相比之下，点状von Frey细丝的力阈值在RAS和SAS中没有区别，在PC中最低。在人体内诱发的感觉强度随着高于阈值的点高度的增加而增加。类似地，猴子RAS中诱发的神经冲动的数量随着斑点高度的增加而增加，RA感受野的宽度也是如此。笔划速度在10~40 mm/S之间的变化，以及点片施加在皮肤上的垂直力的变化，都不会改变15微米高的点所引起的感觉大小或RAS中诱发的脉冲数量。然而，卒中速度从10 mm/S降低到1.5 mm/min，提高了感觉检测阈值，对于15微米高的圆点，感觉幅度、RAS中的脉冲数量和RA感受野的宽度都降低了。据推测，导致RA激活的力学事件是皮肤隆起区的横向变形。为了支持这一点，当一个点划过乳头脊而不是沿着乳头脊时，在RAS中由该点引起的冲动数量更多。此外，在某些刺激条件下，观察到在RA中每个动作电位的出现与点的前沿穿过乳头脊的峰部之间的对应关系。结论是，仅RAS的反应就能解释用指垫探测光滑表面上最小高度的点的感觉能力。
The capacities of humans to detect the presence of a single raised dot of 550 micron diameter on a smooth plate and to judge the magnitude of evoked sensation were determined for dots of different heights, stroked at different velocities across the passive fingerpad. Evoked responses to the same stimuli were recorded from single, slowly adapting (SA), rapidly adapting (RA), and Pacinian (PC) mechanoreceptive peripheral nerve fibers innervating the fingerpad of anesthetized macaque monkeys. When the stroke velocity was 10 mm/s, dot height detection thresholds, as determined from measurements of detection sensitivity were between 1 and 3 microns for all human observers. From fiber recordings in monkeys, the RAs had dot height thresholds of 2-4 microns, i.e., within the range of human detection thresholds. The dot height thresholds were 8 microns or greater for SAs and 21 micron or greater for PCs. In contrast, force thresholds for punctate von Frey filaments did not differ for RAs and SAs and were lowest for PCs. The magnitude of sensation evoked in human increased with increases in dot height above threshold. Similarly, the number of nerve impulses evoked in monkey RAs increased with dot height as did the widths of RA receptive fields. Neither changes in stroke velocity from 10 to 40 mm/s nor changes in vertical force applied by the dot plate to the skin altered sensory magnitude evoked by a 15-microns high dot or the number of impulses evoked in RAs. However, a decrease in stroke velocity from 10 to 1.5 mm/s elevated sensory detection thresholds and, for the 15-microns high dot, decreased sensory magnitude, the number of impulses in RAs, and the widths of RA receptive fields. It was hypothesized that the mechanical event responsible for activating the RA was the lateral deformation of elevated regions of skin. In support of this, the number of impulses evoked in RAs by a dot was greater when the dot was stroked across, as opposed to along, the papillary ridges. Also, under certain stimulus conditions, a correspondence was observed between the occurrence of each action potential in an RA and the passage of the leading edge of the dot across the peak of a papillary ridge. It is concluded that the responses of RAs alone account for the sensory capacity to detect a dot of minimal height on a smooth surface with the fingerpad.(ABSTRACT TRUNCATED AT 400 WORDS)
登录
查看更多内容
二维超声心动图与门控放射性核素心室造影评估急性心肌梗死整体和局部左心室功能的比较。
影响因子：
24
作者：
VanReet,RE;Quinones,MA;Poliner,LR;Nelson,JG;Waggoner,AD;Kanon,D;Lubetkin,SJ;Pratt,CM;WintersJr,WL
通讯作者：
WintersJr,WL
20世纪80年代以来家庭消费和资产的实证分析
DOI：
--
发表时间：
2006
期刊：
総務省統計研修所 リサーチペーパー 第5号
影响因子：
--
作者：
元山 斉;山口 幸三;ryoko Morozumi;美添泰人・荒木万寿夫
通讯作者：
美添泰人・荒木万寿夫
影响因子：
37.8
作者：
HEGER, JJ;WEYMAN, AE;FEIGENBAUM, H
通讯作者：
FEIGENBAUM, H
正常和肥大的人类左心室的壁应力。
影响因子：
2.8
作者：
W. P. Hood;C. Rackley;E. Rolett
通讯作者：
E. Rolett
实验性冠状动脉狭窄中的二维超声心动图：II. 严重冠状动脉狭窄时收缩期壁变薄与局部心肌灌注的关系
影响因子：
37.8
作者：
N. Pandian;R. Kieso;R. Kerber
通讯作者：
R. Kerber