Antibiotic resistance and genotypic characterization by PFGE of clinical and environmental isolates of enterococci
Antibiotic resistance and genotypic characterization by PFGE of clinical and environmental isolates of enterococci
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DOI：
10.1111/j.1574-6968.2001.tb10758.x
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发表时间：
2001-07-24
影响因子：
2.1
通讯作者：
Baldassarri, L
中科院分区：
文献类型：
--
作者：
Dicuonzo, G;Gherardi, G;Baldassarri, L
对来自罗马、意大利临床和非人源的54株粪肠球菌和20株屎肠球菌进行抗生素耐药性和脉冲场凝胶电泳（PFGE）鉴定。屎肠球菌对万古霉素、替考拉宁、氨苄西林和环丙沙星的耐药率高于肠球菌。粪肠球菌对氨基糖苷类抗生素的耐药率较高，而肠球菌对氨基糖苷类抗生素的耐药率较高。粪便。多重耐药主要见于临床分离株，但也见于环境分离株。观察到临床和环境分离株之间共有的共同基因型，然而，大多数分离株作为独特的来源特异性克隆出现。几种PFGE类型与其抗生素耐药模式的共同特征相关;还注意到病房之间和病房内的克隆传播证据。这是第一份报告表明克隆之间的相关性人类和环境肠球菌分离在意大利。(C)2001年由Elsevier Science BN出版。代表欧洲微生物学会联合会。
Fifty-four Enterococcus faecalis and 20 Enterococcus faecium isolates from clinical and non-human sources in Rome, Italy, were characterized by antibiotic resistance and pulsed field gel electrophoresis (PFGE). Resistance to vancomycin, teicoplanin, ampicillin, and ciprofloxacin was more frequent in E faecium than in E. faecalis, whereas high-level resistance to aminoglycoside was found primarily in E. faecalis. Multi-resistance was found primarily among clinical isolates, but was also observed among environmental isolates. Common genotypes shared among clinical and environmental isolates were observed, however, the majority of isolates occurred as unique, source-specific clones. Several PFGE types were associated with shared features in their antibiotic resistance patterns; evidences of clonal spread between and within wards were also noted. This is the first report indicating clonal relatedness between human and environmental enterococci isolated in Italy. (C) 2001 Published by Elsevier Science BN. on behalf of the Federation of European Microbiological Societies.