COMPLETION PNEUMONECTOMY - INDICATIONS, COMPLICATIONS, AND RESULTS
COMPLETION PNEUMONECTOMY - INDICATIONS, COMPLICATIONS, AND RESULTS
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DOI：
10.1016/s0003-4975(10)65886-9
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发表时间：
1988-08-01
影响因子：
4.6
通讯作者：
PAYNE, WS
中科院分区：
文献类型：
--
作者：
MCGOVERN, EM;TRASTEK, VF;PAYNE, WS
从1958年到1985年，共有113例连续患者完成了全肺切除术（CP）。肺切除术导致CP的适应症为64例肺癌（LC）、20例肺转移瘤（PM）和29例良性肺病（BLD）。手术死亡率为12.4%（14例死亡），但根据CP的适应症而有所不同。LC的死亡率为9.4%，PM为0%，BLD为27.6%。43例患者（38.1%）发生严重并发症（64例LC中26例，40.6%; 20例PM中1例，5.0%; 29例BLD中16例，55.2%）。LC患者的5年生存率为26.4%，但根据分期不同而不同。PM患者的5年生存率为40.8%，BLD为27.2%。我们的结论是，CP治疗BLD具有显著的手术死亡率和发病率，通常是由于肺门结构周围的强烈反应和并发的活动性感染或瘘。相比之下，LC和PM的CP可以以低死亡率，可接受的发病率和令人满意的长期生存率进行。
From 1958 through 1985, a total of 113 consecutive patients had completion pneumonectomy (CP). Indications for pulmonary resection resulting in CP were lung cancer (LC) in 64 patients, pulmonary metastases (PM) in 20, and benign lung disease (BLD) In 29. Operative mortality was 12.4% (14 deaths) but varied according to the indication for CP. Mortality was 9.4% for LC, 0% for PM, and 27.6% for BLD. Forty-three patients (38.1%) had major complications (26 of 64 with LC, 40.6%; 1 of 20 with PM, 5.0%; and 16 of 29 with BLD, 55.2%). Five-year actuarial survival for patients with LC was 26.4% but varied according to stage. Five-year survival for patients with PM was 40.8% and with BLD was 27.2%. We conclude that CP for BLD carries marked operative mortality and morbidity, usually due to intense reaction around hilar structures and concurrent active infection or fistula. In contrast, CP for LC and PM can be performed with low mortality, acceptable morbidity, and gratifying long-term survival.