Multiphasic perfusion CT in acute middle cerebral artery ischemic stroke: Prediction of final infarct volume and correlation with clinical outcome
Multiphasic perfusion CT in acute middle cerebral artery ischemic stroke: Prediction of final infarct volume and correlation with clinical outcome
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DOI：
10.3348/kjr.2002.3.3.163
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发表时间：
2002-07-01
影响因子：
4.8
通讯作者：
Lee, SJ
中科院分区：
文献类型：
--
作者：
Yi, CA;Na, DG;Lee, SJ
目的：评估多相灌注CT在预测最终梗死体积中的效用，以及CT成像显示的病灶体积与未接受溶栓治疗的急性缺血性脑卒中患者临床结局之间的关系。 材料与方法：35名患者在脑卒中发病后6小时内接受了多相灌注CT。基线非增强螺旋 CT 扫描后，以 3 mL/秒的速度注射 90 mL 造影剂后 20、34、48 和 62 秒获得对比增强 CT 扫描。从连续 CT 图像中获得 CT 峰值和总灌注图，并将 CT 显示的初始病变体积与最终梗塞体积和临床评分进行比较。 结果：总体而言，CT 峰值灌注图上看到的病变体积与最终梗塞体积相关性最强（R-2=0.819，p
Objective: To assess the utility of multiphasic perfusion CT in the prediction of final infarct volume, and the relationship between lesion volume revealed by CT imaging and clinical outcome in acute ischemic stroke patients who have not undergone thrombolytic therapy.Materials and Methods: Thirty-five patients underwent multiphasic perfusion CT within six hours of stroke onset. After baseline unenhanced helical CT scanning, contrast-enhanced CT scans were obtained 20, 34, 48, and 62 secs after the injection of 90 mL contrast medium at a rate of 3 mL/sec. CT peak and total perfusion maps were obtained from serial CT images, and the initial lesion volumes revealed by CT were compared with final infarct volumes and clinical scores.Results: Overall, the lesion volumes seen on CT peak perfusion maps correlated most strongly with final infarct volumes (R-2=0.819, p