The relationship between germinal cells and serum FSH levels in males with infertility.
The relationship between germinal cells and serum FSH levels in males with infertility.
复制标题
男性不育症生殖细胞与血清FSH水平的关系。
DOI：
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发表时间：
1974
影响因子：
5.8
通讯作者：
B. Hudson
中科院分区：
文献类型：
--
作者：
D. de Kretser;H. Burger;B. Hudson
本文研究了49例不育症患者睾丸活检标本中特定类型生殖细胞与血清FSH水平的关系。通过计数25个不同曲细精管横截面中的生殖细胞，对睾丸活检进行定量分析。这些定量组织学研究表明，血清FSH水平与每个小管的精原细胞，初级精母细胞，早期和晚期精子细胞的平均数量之间存在显着的相关性，当每组单独服用。血清FSH水平与Sertoli细胞平均数之间无明显相关性。结果表明，获得的最显着的相关性是精原细胞的平均数量和血清FSH水平之间，并表明，更成熟的生殖细胞和FSH水平之间的相关性可能是由于前者的关系。
ABSTRACT The relationship between specific types of germinal cells in testicular biopsy specimens and serum FSH levels has been investigated in 49 men with infertility. Testicular biopsies were analysed quantitatively by counting the germinal cells present in cross-sections of 25 different seminiferous tubules. These quantitative histological studies demonstrated that a significant correlation exists between serum FSH levels and the mean number of spermatogonia, primary spermatocytes, early and late spermatids per tubule when each group is taken singly. No correlation was evident between the serum FSH level and the mean number of Sertoli cells. The results indicate that the most significant correlation obtained was between the mean number of spermatogonia and serum FSH levels and suggests that correlations obtained between the more mature germinal cells and FSH levels may result from the former relationship.