A modeling framework to estimate patellofemoral joint cartilage stress in vivo
A modeling framework to estimate patellofemoral joint cartilage stress in vivo
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DOI：
10.1249/01.mss.0000176686.18683.64
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发表时间：
2005-11-01
期刊：
影响因子：
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通讯作者：
Delp, SL
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文献类型：
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作者：
Besier, TF;Gold, GE;Delp, SL
目的：髌股（PF）疼痛在运动员中很常见，可能是由于股骨或髌骨软骨应力增加导致软骨下骨应力增加所致。本文提出了一种估算PF关节软骨应力的建模管道，方法：该建模管道采用有限元法计算PF关节软骨的应力和应变。模型输入包括来自磁共振成像（MRI）的骨骼和软骨的精确几何表示、软骨材料属性以及来自EMG驱动的肌肉骨骼模型的肌肉力估计。使用PF关节接触面积和从直立、负重MRI测量的髌骨方向进行确认。从一个积极的，无痛的主题的初步数据说明了建模管道计算软骨应力在静态squake.Results：准静态有限元模拟重现髌骨的方向在2.1 mm内，并预测PF关节接触面积在2.3%。八面体剪切应力在髌骨软骨的中央、外侧最高，峰值为2.5 MPa。股骨软骨中的相应应力仅为2.0 MPa。然而，峰值静水压力较高的股骨软骨（3.5 MPa）比髌骨软骨（2.3 MPa）。结论：本文提出的方法提供了一种新的方法来计算PF关节软骨应力在体内。未来的工作将使用这个建模管道，以进一步了解PF疼痛和潜在的康复策略。
Purpose: Patellofemoral (PF) pain is common among athletes and may be caused by increased subchondral bone stress as a result of increased stress in the cartilage of the femur or patella. This article presents a modeling pipeline to estimate in vivo cartilage stress in the PF joint.Methods: The modeling pipeline uses the finite element method to calculate stresses and strains in the PF joint cartilage. Model inputs include an accurate geometrical representation of the bones and cartilage from magnetic resonance imaging (MRI), cartilage material properties, and an estimate of muscle forces from an EMG-driven musculoskeletal model. Validation is performed using PF joint contact area and patellar orientation measured from upright, weight-bearing MRI. Preliminary data from an active, pain-free subject illustrate the modeling pipeline to calculate cartilage stress during a static squat.Results: The quasistatic finite element simulation reproduced the orientation of the patella to within 2.1 mm and predicted the PF joint contact area to within 2.3%. Octahedral shear stresses were highest in the central, lateral aspect of the patella cartilage with a peak of 2.5 MPa. The corresponding stresses in the femoral cartilage reached only 2.0 MPa. However, peak hydrostatic pressures were higher within the femoral cartilage (3.5 MPa) than the patellar cartilage (2.3 MPa).Conclusion: The methods presented in this article offer a novel approach to calculate PF joint cartilage stress in vivo. Future efforts will use this modeling pipeline to further our knowledge of PF pain and potential rehabilitation strategies.