Influence of exercise on strength of medial collateral knee ligaments of dogs.
Influence of exercise on strength of medial collateral knee ligaments of dogs.
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运动对犬膝关节内侧副韧带强度的影响。
DOI：
10.1152/ajplegacy.1970.218.3.894
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发表时间：
1970
期刊：
影响因子：
--
通讯作者：
T. Tcheng
中科院分区：
文献类型：
--
作者：
C. Tipton;S. L. James;W. Mergner;T. Tcheng
方法选用体重15 ~ 20 kg、1岁以上的小型杂种犬。每个人都接受了兽医的检查，接受了抗寄生虫药，浸在氯化溶液中以控制寄生虫，接种了犬瘟热和肝炎疫苗，并隔离了1周。除了动物护理单位的工作人员提供的照顾外，这些动物每天都要接受检查，每周都要称重。为了预防与感染相关的问题，狗接受了盐酸四环素（Sumycin, ER Squibb and Sons，纽约市）（125 " g/只），肌肉注射60万单位苄星青霉素g（比西林），局部应用2%呋拉辛粉末（Eaton Laboratories, Norwich， NY）。它们被安置在30英寸x 30英寸x 25英寸的笼子里，并保持在22摄氏度的室温下。用于大鼠（41,43）的测试设备和程序经过修改，以确定狗的韧带强度（图1）。从本质上讲，这意味着用戊巴比妥钠（300毫克/公斤）牺牲狗，并迅速切除后腿。跖肌、腓肠肌和指长伸肌也被解剖并在分析天平上称重。切除关节周围的软组织，使关节囊和韧带完好无损。将骨-胶囊-骨制备物置于测试装置中，记录股骨与胫骨的空间关系。然后移除准备物，除内侧副韧带外，仔细移除所有剩余组织。然后将膝关节准备物送回测试设备，将其置于股骨和胫骨之间成120-125英寸的角度。这个角度是在未麻醉的站立犬获得x线片后选择的。股骨被连接到固定传感器（Schaevitz-Bytrex Inc., Waltham, Mass）。（JP系列），胫骨为-
METHODSMale mongrel dogs were used that were between 15-20 kg in weight and more than 1 year of age. Each had been inspected by a veterinarian, received an antihelmintic, dipped in a chlorinated solution to control parasites, immunized for distemper and hepatitis, and quarantined for 1 week. In addition to the care provided by the personnel of the Animal Care Unit, the animals were inspected daily and weighed weekly. To prevent problems associated with infections, the dogs received tetracycline hydrochloride (Sumycin, ER Squibb and Sons, New York City)(125 “g/dog), intramuscular injections of 600,000 units of benzathine penicillin G (Bicillin), and topical applications of 2% Furacin powder(Eaton Laboratories, Norwich, NY). They were housed in 30 inch x 30 inch x 25 inch cages and maintained at a room temperature of 22 C. The testing apparatus and procedures used for rats (41, 43) was modified to determine the strength of the ligaments from dogs (Fig. 1). In essence, this meant that the dogs were sacrificed with sodium pentobarbital(300 mg/kg) and the hindlegs quickly removed. The plantaris, gastrocnemius and extensor digitorium longus muscles were also dissected and weighed on an analytical balance. The soft tissues around the joint were removed leaving the capsule and ligaments intact. The bone-capsule-bone preparation was placed into the testing apparatus and the spatial relationship between the femur and tibia recorded. The preparation was then removed and all remaining tissue was carefully removed except the medial collateral ligament. The knee preparation was then returned to the testing apparatus where it was placed at an angle of 120-125” between the femur and the tibia. This angle was selected after roentgenograms were obtained from standing unanesthetized dogs. The femur was attached to the stationary transducer(Schaevitz-Bytrex Inc., Waltham, Mass., JP series) while the tibia was at-