LOCAL ANALGESIA WITHOUT ANESTHESIA USING PERIPHERAL PERINEURAL MORPHINE INJECTIONS
LOCAL ANALGESIA WITHOUT ANESTHESIA USING PERIPHERAL PERINEURAL MORPHINE INJECTIONS
复制标题
DOI：
10.1213/00000539-198705000-00008
复制
发表时间：
1987-05-01
影响因子：
5.7
通讯作者：
SCHNAPP, M
中科院分区：
文献类型：
--
作者：
MAYS, KS;LIPMAN, JJ;SCHNAPP, M
25例慢性疼痛患者接受神经阻滞治疗。根据采用标准神经阻滞技术进行手术麻醉所需的局麻药量，将患者分为A、B两组。A组16例，小神经分布区疼痛，阻滞剂量不超过5ml，采用0.5%布比卡因或0.02%吗啡随机、双盲交叉阻滞。B组9例，同时注入生理盐水30 ml，肌内注射1 ml。以随机、双盲的方式将吗啡（6 mg）加入其中一次注射。随后通过替代途径使用吗啡进行第二对注射。在统计学上，神经周围吗啡比肌内吗啡或神经周围布比卡因提供更持久的疼痛缓解。
Twenty-five patients with chronic pain were treated with nerve blocks. They were divided into two groups, A and B, according to the volume of local anesthetic required for surgical anesthesia by standard nerve block techniques. The 16 patients in group A had pain in the distribution of small nerves, which could be blocked with 5 ml or less. They were blocked in a random, double-blind crossover fashion using 0.5% bupivacaine or 0.02% morphine. The nine patients in group B were injected simultaneously with saline, 30 ml perineurally and 1 ml intramuscularly. Morphine (6 mg) was added, in a random, double-blind fashion, to one of the injections. A second pair of injections was subsequently done, using morphine by the alternative route. Perineural morphine provided statistically longer lasting pain relief than did either intramuscular morphine or perineural bupivacaine.